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Showing 1–6 of 6 results

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Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

Suzana Markolovic
Qinqin Zhuang
Christopher J. Schofield
Amendments and Corrections27 Jun 2018
Nature Chemical Biology

Volume: 14, P: 988
USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7

Though ubiquitin is known to broadly influence endosomal trafficking, few ubiquitin-utilizing enzymes targeting endosomal regulators are known. Here, the authors find that the deubiquitylating enzyme (DUB) USP32 influences endosomal membrane dynamics by deubiquitinating Rab7.

Aysegul Sapmaz
Ilana Berlin
Huib Ovaa
ResearchOpen Access29 Mar 2019
Nature Communications

Volume: 10, P: 1-18
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

Structural, biochemical and cellular studies reveal JMJD7 to be a Jumonji-C oxygenase that catalyzes (3S)-lysyl hydroxylation of the translation factor family of GTPases, DRG1 and DRG2.

Suzana Markolovic
Qinqin Zhuang
Christopher J. Schofield
Research18 Jun 2018
Nature Chemical Biology

Volume: 14, P: 688-695
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

Transcription regulation requires recruitment of different epigenetic regulators to the chromatin. Here the authors provide evidence that an H3K36me3 reader PWWP2A forms a variant NuRD complex and plays a role in regulating transcription and histone acetylation dynamics.

Tianyi Zhang
Guifeng Wei
Neil Brockdorff
ResearchOpen Access18 Sept 2018
Nature Communications

Volume: 9, P: 1-14
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage

Ryotaro Nishi
Paul W. G. Wijnhoven
Benedikt M. Kessler
ResearchOpen Access17 Dec 2018
Scientific Reports

Volume: 8, P: 1-15
miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration

Cheen P. Khoo
Maria G. Roubelakis
Suzanne M. Watt
ResearchOpen Access09 Mar 2017
Scientific Reports

Volume: 7, P: 1-14