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Showing 1–3 of 3 results
Advanced filters: Author: Reshmi Ramakrishnan Clear advanced filters
  • Natural killer cells of acute myeloid leukaemia patients lack cytotoxic activity. Here the authors show that these cells have elevated GSK3β, and that its inhibition prolongs survival of mice transplanted with human AML and stimulates NK cytotoxicity via increased adhesion of NK cells to their targets.

    • Reshmi Parameswaran
    • Parameswaran Ramakrishnan
    • David N. Wald
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11
  • Aggregation is sequence-specific and nucleated by short aggregating protein segments (APR). Here authors use a multidisciplinary approach to show that in E.coli some frequently occurring APRs lead to protein aggregation and ultimately bacterial cell death, which could serve as antibacterial strategy.

    • Ladan Khodaparast
    • Laleh Khodaparast
    • Joost Schymkowitz
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15