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Showing 1–5 of 5 results
Advanced filters: Author: Reyn Kenyon Clear advanced filters

  • FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

    • Sven Dorkenwald
    • Arie Matsliah
    • Meet Zandawala
    ResearchOpen Access
    Nature
    Volume: 634, P: 124-138

  • Our incomplete understanding of how pancreatic beta cells form limits the generation of beta-like cells from human pluripotent stem cells (hPSC). Here, the authors identify a ROCKII inhibitor H1152 as increasing insulin secreting cells from hPSCs and improving beta-cell maturation on transplantation in vivo.

    • Zaniar Ghazizadeh
    • Der-I Kao
    • Shuibing Chen
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • Diseases such as diabetes and Parkinson's manifest based on interactions between genes and environment. Here, the authors find among a panel of cell types that propargite, a common pesticide, induces pancreatic β-cell and dopamine neuron death and that loss of the gene GSTT1 confers hypersensitivity.

    • Ting Zhou
    • Tae Wan Kim
    • Shuibing Chen
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • Zika virus (ZIKV) can persist for months in semen and sperm. Here, the authors show that germ cells, compared to other cell types in the reproductive tract, are most susceptible to ZIKV and produce high levels of progeny virus, which coincides with decreased expression of the interferon-stimulated gene Ifi44l.

    • Christopher L. Robinson
    • Angie C. N. Chong
    • Shuibing Chen
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11