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Showing 1–4 of 4 results
Advanced filters: Author: Rickesha Bell Clear advanced filters

  • Past intestinal distress is associated with diminished social behavior in mice. Here, the authors show that treatment with microbiota members that are enriched in neurotypical people versus people with ASD can ameliorate colitis severity and associated sociability deficits.

    • D. Garrett Brown
    • Michaela Murphy
    • June L. Round
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • Studies of mouse and human IgA responses against Candida albicans and other common fungal species show that host adaptive immunity selects for fungal effectors that promote commensalism and prevent intestinal disease.

    • Kyla S. Ost
    • Teresa R. O’Meara
    • June L. Round
    Research
    Nature
    Volume: 596, P: 114-118

  • In young mice, antigens from the gut microbiota are trafficked by CX3CR1+ dendritic cells from the gut to the thymus, where they induce the expansion of T cells that are specific to commensal microorganisms.

    • Daniel F. Zegarra-Ruiz
    • Dasom V. Kim
    • Gretchen E. Diehl
    Research
    Nature
    Volume: 594, P: 413-417

  • Composition of the gut microbiota is regulated by IgA antibodies which are produced under the control of MHCII-restricted B cells. Here the authors show that MHCII polymorphisms sculpt bacterial composition of the gut, which influences a host’s susceptibility to enteric Salmonellainfection.

    • Jason L. Kubinak
    • W. Zac Stephens
    • June L. Round
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13