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Showing 1–3 of 3 results
Advanced filters: Author: Rob van Nues Clear advanced filters

  • Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently accumulate.

    • Stefan Gerhardy
    • Michaela Oborská-Oplová
    • Vikram Govind Panse
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Ribosome biogenesis is a dynamic process that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrangements. Here the authors apply ChemModSeq, a high-throughput RNA structure probing method, to quantitatively measure changes in RNA flexibility during the nucleolar stages of 60S assembly in yeast.

    • Elena Burlacu
    • Fredrik Lackmann
    • Sander Granneman
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • Protein RNA interactions are dynamic and regulated in response to environmental changes. Here the authors describe ‘kinetic CRAC’, an approach that allows time resolved analyses of protein RNA interactions with minute time point resolution and apply it to gain insight into the function of the RNA-binding protein Nab3.

    • Rob van Nues
    • Gabriele Schweikert
    • Sander Granneman
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-18