In this instructive Review, Skelding et al. explain how the recently published Haplotype Genetic Map (HapMap) has the potential to revolutionize our genetic discoveries. By cataloguing common haplotypes in the human genome, the HapMap will help elucidate the multiple genetic variants underlying common complex processes, such as in-stent restenosis. Jargon-free and informative, this Review provides insight into the relevance of HapMap to cardiovascular practice.
- Kimberly A Skelding
- Glenn S Gerhard
- David R Holmes Jr