Acuña et al. develop mini-GRID to optimally deliver spatially fractionated radiation therapy using a flattening filter-free linear accelerator. Authors demonstrate its feasibility, and reduction in side effects on normal tissues through longitudinal MRI imaging, behavioural tests, histopathology, and infrared microspectroscopy in rat brain tissue.
- M. Isabel Acuña
- Charlotte Lamirault
- Yolanda Prezado