Immunoglobulin G (IgG) is the main isotype of antibody in human blood. Here the authors describe 14 genetic variants that affect IgG levels in blood. The data provide new insight into the regulation of humoral immunity that could be useful in the development of antibody-based therapeutics.
- Thorunn A. Olafsdottir
- Gudmar Thorleifsson
- Kari Stefansson
