The Tec family tyrosine kinase, Itk, is a component of the T-cell receptor essential for optimal Th2 responses in vivo. Here the authors show in human cells and mouse models that Itk is also needed for the production of IL-9, an important contributor to allergic asthma.
- Julio Gomez-Rodriguez
- Françoise Meylan
- Pamela L. Schwartzberg
