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Erratum: Mapping and elucidating the function of modified bases in DNA

Eun-Ang Raiber
Robyn Hardisty
Shankar Balasubramanian
Amendments and Corrections11 Oct 2017
Nature Reviews Chemistry

Volume: 1, P: 1
Mapping and elucidating the function of modified bases in DNA

Research into naturally occurring chemically modified DNA bases has been invigorated by new chemical and enzymatic methods that, when coupled with sequencing approaches, enable us to detect and decode them. These techniques will support a better understanding of the role of chemically modified DNA bases in normal physiology and disease.

Eun-Ang Raiber
Robyn Hardisty
Shankar Balasubramanian
Reviews06 Sept 2017
Nature Reviews Chemistry

Volume: 1, P: 1-13
5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells

A series of in vitro and in vivo studies has now shown that 5fC is linked to increased nucleosome occupancy and stability. Moreover, there is evidence that Schiff base formation between histones and 5fC impacts RNA polymerase II transcription activity in mouse embryonic stem cells.

Eun-Ang Raiber
Guillem Portella
Shankar Balasubramanian
Research22 Oct 2018
Nature Chemistry

Volume: 10, P: 1258-1266

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