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Showing 1–4 of 4 results

Advanced filters: Author: Rocio Montes de Oca Clear advanced filters

SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin

Geneviève Almouzni and colleagues report that SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin in mouse. They identify long nuclear non-coding transcripts at major satellite repeats and show that they specifically associate with SUMO-modified HP1 proteins.

Christèle Maison
Delphine Bailly
Geneviève Almouzni
Research13 Feb 2011
Nature Genetics

Volume: 43, P: 220-227
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

David M. Berman
Sunil S. Karhadkar
Philip A. Beachy
Research14 Sept 2003
Nature

Volume: 425, P: 846-851
Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues

Paul B. Noto
Timothy W. Sikorski
Caretha L. Creasy
ResearchOpen Access17 Dec 2020
Scientific Reports

Volume: 10, P: 1-19
Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing

Sarah V. Gerhart
Wendy A. Kellner
Olena Barbash
ResearchOpen Access26 Jun 2018
Scientific Reports

Volume: 8, P: 1-15