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Showing 1–3 of 3 results
Advanced filters: Author: Rodrigo Cataldi Clear advanced filters

  • Cataldi et al. investigates the impact of the dopamine derivative DOPAL on the Aβ peptide oligomer formation. They report that DOPAL promotes the formation of stable Aβ oligomers that exert toxicity on neuroblastoma cells by increasing cytosolic calcium levels and generating reactive oxygen species. This study connects Aβ aggregation with processes regulating cellular homeostasis in the brain.

    • Rodrigo Cataldi
    • Sean Chia
    • Michele Vendruscolo
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-10

  • The World Health Organization (WHO) blueprint for dementia research provides a roadmap to addressing the challenges in the field and reshaping our approach to dementia research. This Comment focuses on how to operationalize the drivers of research highlighted in the blueprint to make research more equitable, impactful and global.

    • Rodrigo Cataldi
    • Perminder S. Sachdev
    • Tarun Dua
    Comments & Opinion
    Nature Aging
    Volume: 3, P: 469-471