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Showing 1–3 of 3 results
Advanced filters: Author: Roger Rubio-Sánchez Clear advanced filters

  • A common genetic cause of Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is expansion of the intronic hexanucleotide repeat (GGGGCC)n in C9orf72. Here the authors reveal that the RNA (GGGGCC)n expansion repeat associated with ALS/FTD can generate condensates in the absence of proteins, highlighting the potential relevance of targeting RNA-structures to treat neurodegenerative diseases.

    • Federica Raguseo
    • Yiran Wang
    • Marco Di Antonio
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Lipid membrane disruption is often associated with disease but is also essential to a range of biosensing and therapeutic techniques. Here, the authors report on the development of DNA-based particles that, upon exposure to an external cue, can aggregate, disrupt lipid membranes, and arrest the motion of bacteria.

    • Michal Walczak
    • Ryan A. Brady
    • Lorenzo Di Michele
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Eighteen years after its inception, the international Genetically Engineered Machine competition has catalyzed the infusion of synthetic biology with interdisciplinary fundamental and translational research, as well as with inspired young scientists.

    • Ashwin K. Jainarayanan
    • Anastasios Galanis
    • Roger Rubio-Sánchez
    Comments & Opinion
    Nature Biotechnology
    Volume: 39, P: 1599-1601