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Showing 1–4 of 4 results

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Publisher Correction: IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function

Chiara Montemurro
Hiroshi Nomoto
Slavica Tudzarova
Amendments and CorrectionsOpen Access31 Jul 2019
Nature Communications

Volume: 10, P: 1
IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function

Type 2 diabetes is associated with islet amyloid deposits derived from islet amyloid polypeptide (IAPP) expressed by β-cells. Here the authors show that IAPP misfolded protein stress induces the hypoxia inducible factor 1 alpha injury repair pathway and activates survival metabolic changes mediated by PFKFB3.

Chiara Montemurro
Hiroshi Nomoto
Slavica Tudzarova
ResearchOpen Access18 Jun 2019
Nature Communications

Volume: 10, P: 1-17
Publisher Correction: Cell types of origin of the cell-free transcriptome

Sevahn K. Vorperian
Mira N. Moufarrej
Stephen R. Quake
Amendments and CorrectionsOpen Access28 Mar 2022
Nature Biotechnology

Volume: 40, P: 974
Cell types of origin of the cell-free transcriptome

Cell types affected by various diseases are inferred from cell-free RNA.

Sevahn K. Vorperian
Mira N. Moufarrej
Stephen R. Quake
ResearchOpen Access07 Feb 2022
Nature Biotechnology

Volume: 40, P: 855-861

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