Nature Search

Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning

Sarah Dandou
Kriti Amin
Romain M. Larive
ResearchOpen Access09 Jul 2025
npj Precision Oncology

Volume: 9, P: 1-9
Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease

Ras family members have critical roles in many types of tumours but the role of R-Ras2 in cancer is unclear. Here the authors show that R-Ras2 is important in both the formation of breast primary tumours and metastasis to the lung.

Romain M. Larive
Giulia Moriggi
Xosé R. Bustelo
Research14 May 2014
Nature Communications

Volume: 5, P: 1-14
MelanoDB: A dataset of clinical and molecular features of patients with advanced melanoma treated with MAPK inhibitors

Sarah Dandou
Julie A. Vendrell
Romain M. Larive
ResearchOpen Access04 Jul 2025
Scientific Data

Volume: 12, P: 1-14
SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2

SLAP is an adaptor protein that negatively regulates receptor signalling, but its involvement in cancer has not been described. In this study, Naudin et al. demonstrate that SLAP negatively regulates the receptor EphA2 in a Src-dependent manner and is reduced in expression in colorectal cancer.

Cécile Naudin
Audrey Sirvent
Serge Roche
Research24 Jan 2014
Nature Communications

Volume: 5, P: 1-15
Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms

L. Francisco Lorenzo-Martín
Carmen Citterio
Xosé R. Bustelo
ResearchOpen Access07 Aug 2018
Oncogene

Volume: 38, P: 209-227

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Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning

Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease

MelanoDB: A dataset of clinical and molecular features of patients with advanced melanoma treated with MAPK inhibitors

SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2

Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms

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