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Advanced filters: Author: Romila Mascarenhas Clear advanced filters

  • B12-dependent human methylmalonly-CoA mutase (MMUT) requires the chaperone MMAA. The authors report the crystal structure of MMUT-MMAA, which shows a MMAA-driven conformational change in MMUT involved n B12 loading and repair and helps explain the effects of disease-causing MMAA-MMUT interface mutations.

    • Romila Mascarenhas
    • Markus Ruetz
    • Ruma Banerjee
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11