Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Nature Communications (1)
Nature Cell Biology (1)
Nature (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (3)

Subject Check one or more subjects to show results from those subjects only.

Biochemistry
Biophysics
Microbiology
Molecular biology

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–3 of 3 results

Advanced filters: Author: Rongdiao Liu Clear advanced filters

PRMT3 reverses HIV-1 latency by increasing chromatin accessibility to form a TEAD4-P-TEFb-containing transcriptional hub

The mechanism of HIV-1 latency reversal remains unclear. The authors suggest that PRMT3 drives the reversal by enhancing chromatin accessibility to form a transcriptional hub containing TEAD4 and P-TEFb at the viral promoter.

Xinyu Wang
Yuhua Xue
Dan Yu
ResearchOpen Access15 May 2025
Nature Communications

Volume: 16, P: 1-18
Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage

Fu, et al. report that PARP1-dependent poly(ADP-ribsoyl)ation of the P-TEFb subunit CycT1 suppresses its phase separation, which prevents its interaction partner CDK9 from hyperphosphorylating RNA polymerase II and thereby blocks transcription.

Huanyi Fu
Rongdiao Liu
Qiang Zhou
Research07 Apr 2022
Nature Cell Biology

Volume: 24, P: 513-525
Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II

The histidine-rich domain of cyclin T1 promotes phase separation into liquid droplets, which facilitates the hyperphosphorylation of the C-terminal domain repeats of RNA polymerase II.

Huasong Lu
Dan Yu
Qiang Zhou
Research30 May 2018
Nature

Volume: 558, P: 318-323