Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–13 of 13 results
Advanced filters: Author: Ronit Nir Clear advanced filters

  • Chemiluminescence imaging can be applied for the in vivo and in vitro assessment of biological activity. This Review discusses the design, mode of action and application of chemiluminescent probes for the detection of the activity and presence of enzymes and analytes in cancerous tissue.

    • Rachel Blau
    • Omri Shelef
    • Ronit Satchi-Fainaro
    Reviews
    Nature Reviews Bioengineering
    Volume: 1, P: 648-664

  • A method termed ac4C-seq is introduced for the transcriptome-wide mapping of the RNA modification N4-acetylcytidine, revealing widespread temperature-dependent acetylation that facilitates thermoadaptation in hyperthermophilic archaea.

    • Aldema Sas-Chen
    • Justin M. Thomas
    • Schraga Schwartz
    Research
    Nature
    Volume: 583, P: 638-643

  • Here, Noy-Porat, Makdasi et al. report the isolation of a panel of neutralizing mAbs selected against SARS-CoV-2 receptor-binding domain (RBD) from a phage display library constructed based on patient samples collected in the acute phase of the disease, which show efficient neutralizing activities against authentic virus in vitro.

    • Tal Noy-Porat
    • Efi Makdasi
    • Ronit Rosenfeld
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-7

  • In this study, the authors show that a single dose of a combination of two human-like monoclonal antibodies protect mice in therapeutic treatment against challenges with ectromelia virus and monkeypox virus. Combination treatment provided more effective viral clearance than single antibody treatment.

    • Hadas Tamir
    • Tal Noy-Porat
    • Tomer Israely
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10

  • Human ADAR1 and ADAR2 edit millions of adenosines transcriptome-wide, altering RNA structure. Here the authors show that variations in RNA binding domains influence site-specific editing, enhancing ADAR2-targeted therapeutics.

    • Marlon S. Zambrano-Mila
    • Monika Witzenberger
    • Schraga Schwartz
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • We describe a human DNA methylome atlas based on deep whole-genome bisulfite sequencing, allowing fragment-level analysis of cell-type-specific markers and providing an essential resource for studies of gene regulation and for deconvolution of cell mixtures and liquid biopsies.

    • Netanel Loyfer
    • Judith Magenheim
    • Tommy Kaplan
    ResearchOpen Access
    Nature
    Volume: 613, P: 355-364

  • Interacting cartilage surfaces in synovial joints experience very low levels of friction, allowing unhindered mechanical motion. Here, the authors propose how a synergistic interaction of hyaluronan, lubricin and phospholipids, molecules that are ubiquitous in joints, may lead to this high level of lubrication.

    • Jasmine Seror
    • Linyi Zhu
    • Jacob Klein
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-7

  • Here, using the K18-hACE2 transgenic mice model, the authors report the in vivo efficacy of a fully human neutralizing antibody against SARS-CoV-2 and show that when administered before or up to 3 days post infection, treated mice do not exhibit disease symptoms while 80% of control animals succumb to the infection.

    • Ronit Rosenfeld
    • Tal Noy-Porat
    • Ohad Mazor
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • MiRNAs are known regulators of gene expression. Here the authors perform a large-scale massively parallel reporter assay to investigate the effect of a large number of designed 3′ UTR sequences on reporter expression and asses how miRNA regulatory elements features affect miRNA mediated repression.

    • Ilya Vainberg Slutskin
    • Shira Weingarten-Gabbay
    • Eran Segal
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-18

  • Glioma-associated microglia/macrophages are central drivers of brain tumor pathology. Here the authors characterize the role of the P-selectin/PSGL-1 axis in the cross-talk between glioblastoma cells and microglia/macrophages and show that the therapeutic targeting of P-selectin limits glioblastoma progression in preclinical models.

    • Eilam Yeini
    • Paula Ofek
    • Ronit Satchi-Fainaro
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-22

  • Transcriptome-wide mapping of N1-methyladenosine (m1A) at single-nucleotide resolution reveals m1A to be scarce in cytoplasmic mRNA, to inhibit translation, and to be highly dynamic at a single site in a mitochondrial mRNA.

    • Modi Safra
    • Aldema Sas-Chen
    • Schraga Schwartz
    Research
    Nature
    Volume: 551, P: 251-255