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Showing 1–3 of 3 results
Advanced filters: Author: Roopsha Sengupta Clear advanced filters

  • LSD1 reverses methylation of p53 at lysine 370 to repress p53-mediated transcriptional activation and apoptosis, and to prevent the interaction of p53 with 53BP1.

    • Jing Huang
    • Roopsha Sengupta
    • Shelley L. Berger
    Research
    Nature
    Volume: 449, P: 105-108

  • In mouse embryonic stem cells converted to an epiblast fate in vitro—a state in which the cells can also gain germ cell fate if exposed to the signalling molecule BMP4—the sole expression of the transcription factor NANOG is shown to be sufficient to induce germ cell fate, in the absence of BMP4.

    • Kazuhiro Murakami
    • Ufuk Günesdogan
    • M. Azim Surani
    Research
    Nature
    Volume: 529, P: 403-407