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Showing 1–1 of 1 results
Advanced filters: Author: Rosemary Shoop Clear advanced filters

  • The major site of action for obesity treatments based on GLP1R agonists is at the level of the brainstem where neurons share receptors for GLP-1 and GFRAL. Here, authors show two pathways downstream of GFRAL neurons, which are required for the weight-reducing actions of GDF15 and GLP1RA.

    • Claire H. Feetham
    • Valeria Collabolletta
    • Simon M. Luckman
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16