Nature Search

Lipophilic dye-compatible brain clearing technique allowing correlative magnetic resonance/high-resolution fluorescence imaging in rat models of glioblastoma

Marco Peviani
Giorgia Spano
Letterio S. Politi
ResearchOpen Access21 Oct 2020
Scientific Reports

Volume: 10, P: 1-15
Gene therapy of experimental brain tumors using neural progenitor cells

Sara Benedetti
Barbara Pirola
Gaetano Finocchiaro
Research01 Apr 2000
Nature Medicine

Volume: 6, P: 447-450
Skeletal myogenic potential of human and mouse neural stem cells

Rossella Galli
Ugo Borello
Angelo L. Vescovi
Research01 Oct 2000
Nature Neuroscience

Volume: 3, P: 986-991
Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours

Surgical resection is the primary treatment strategy for glioblastoma multiforme, but the infiltrating nature of the tumour, coupled with its heterogeneity and the presence of the blood–brain barrier that hampers drug delivery, contributes to recurrence and poor prognosis. Here the authors engineer a mechanically flexible mesh that can adhere to the tumour resected cavity and release a combination of nanomedicines and small molecules in a controlled and sustained manner for tumour therapy.

Daniele Di Mascolo
Anna Lisa Palange
Paolo Decuzzi
Research01 Apr 2021
Nature Nanotechnology

Volume: 16, P: 820-829
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

Stefano Pluchino
Angelo Quattrini
Gianvito Martino
Research17 Apr 2003
Nature

Volume: 422, P: 688-694
CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

Paola Bezzi
Maria Domercq
Andrea Volterra
Research01 Jul 2001
Nature Neuroscience

Volume: 4, P: 702-710
Brain tumour stem cells

Do alterations in the neural stem-cell population contribute to brain tumorigenesis? This review address how this knowledge might be used to identify new therapeutic strategies for the treatment of brain tumours, such as glioblastoma multiforme and medulloblastoma.

Angelo L. Vescovi
Rossella Galli
Brent A. Reynolds
Reviews01 Jun 2006
Nature Reviews Cancer

Volume: 6, P: 425-436
Minimal residual disease assessment by multiparameter flow cytometry in transplant-eligible myeloma in the EMN02/HOVON 95 MM trial

Stefania Oliva
Davine Hofste op Bruinink
Pieter Sonneveld
ResearchOpen Access03 Jun 2021
Blood Cancer Journal

Volume: 11, P: 1-9
The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

Ashwin Narayanan
Filippo Gagliardi
Rossella Galli
ResearchOpen Access11 Dec 2018
Cell Death & Differentiation

Volume: 26, P: 1813-1831
Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth

Andrea Balboni
Camilla D’Angelo
Andrea Menegon
ResearchOpen Access03 Sept 2024
Scientific Reports

Volume: 14, P: 1-17
Prevention of atherothrombotic events in patients with diabetes mellitus: from antithrombotic therapies to new-generation glucose-lowering drugs

Patients with diabetes mellitus have a prothrombotic status that increases the risk of cardiovascular events and worsens prognosis after these events. In this Consensus Statement, the Working Group on Thrombosis of the Italian Society of Cardiology proposes antithrombotic strategies for patients with diabetes in various cardiovascular settings.

Giuseppe Patti
Ilaria Cavallari
Raffaele De Caterina
ReviewsOpen Access24 Sept 2018
Nature Reviews Cardiology

Volume: 16, P: 113-130
How to manage neonatal tuberculosis

A Di Comite
S Esposito
Elisabetta Scala
Reviews13 Aug 2015
Journal of Perinatology

Volume: 36, P: 80-85
Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

Tatiana Tiago
Barbara Hummel
Serena Carra
ResearchOpen Access06 May 2021
Cell Death & Disease

Volume: 12, P: 1-19
A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes

The authors developed a novel simplified assay for glioblastoma transcriptional classification on formalin-fixed-paraffin-embedded tissue samples. On such dataset, immunohistochemical profiles, based on expression of a restricted panel of gene classifiers, were integrated by machine learning approach to generate a glioblastoma transcriptional signature based on protein quantification that allowed to efficiently assign transcriptional subgroups to an extended cohort. Correlations with both histopathological features and clinical outcome have been also performed.

Francesca Orzan
Francesca Pagani
Pietro Luigi Poliani
Research13 May 2020
Laboratory Investigation

Volume: 100, P: 1330-1344
A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death

Francesca Minnai
Filippo Biscarini
Francesca Colombo
ResearchOpen Access06 Feb 2024
Scientific Reports

Volume: 14, P: 1-14
Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients

Stefania Mantovani
Sergio Daga
Alessandra Renieri
ResearchOpen Access24 Dec 2021
Genes & Immunity

Volume: 23, P: 51-56

Search

Lipophilic dye-compatible brain clearing technique allowing correlative magnetic resonance/high-resolution fluorescence imaging in rat models of glioblastoma

Gene therapy of experimental brain tumors using neural progenitor cells

Skeletal myogenic potential of human and mouse neural stem cells

Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity

Brain tumour stem cells

Minimal residual disease assessment by multiparameter flow cytometry in transplant-eligible myeloma in the EMN02/HOVON 95 MM trial

The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth

Prevention of atherothrombotic events in patients with diabetes mellitus: from antithrombotic therapies to new-generation glucose-lowering drugs

How to manage neonatal tuberculosis

Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes

A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death

Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients

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