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Showing 1–4 of 4 results

Advanced filters: Author: Ru-Ting Huang Clear advanced filters

Single-cell metabolic imaging reveals a SLC2A3-dependent glycolytic burst in motile endothelial cells

Wu, Harrison and colleagues visualize lactate production at subcellular resolution in migrating endothelial cells and identify hotspots of glycolytic activity, mediated by RhoA and the glucose transporter SLC2A3, that couple cellular energy metabolism with cytoskeleton remodelling and cell motility.

David Wu
Devin L. Harrison
Yun Fang
Research24 May 2021
Nature Metabolism

Volume: 3, P: 714-727
Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization

Pulmonary fibrosis is a major public health problem with unclear mechanism and limited therapeutic options. Here the authors show that a fibroblast-enriched endoplasmic reticulum protein, TXNDC5, promotes pulmonary fibrosis by stabilizing TGFBR1 and show the potential of TXNDC5 as a therapeutic target against pulmonary fibrosis.

Tzu-Han Lee
Chih-Fan Yeh
Kai-Chien Yang
ResearchOpen Access26 Aug 2020
Nature Communications

Volume: 11, P: 1-20
Development and comparison of forecast models of hand-foot-mouth disease with meteorological factors

Tao Fu
Ting Chen
Ji-Min Sun
ResearchOpen Access30 Oct 2019
Scientific Reports

Volume: 9, P: 1-7
4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo

Ran Li
Chang-qiong Xu
Jie Wu
Research11 Dec 2020
Acta Pharmacologica Sinica

Volume: 42, P: 1507-1515

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