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Showing 1–2 of 2 results
Advanced filters: Author: Ruchika Dehinwal Clear advanced filters
  • The pathogen Salmonella Typhimurium increases production of outer membrane vesicles (OMVs) inside acidic vacuoles of host cells, but the mechanisms are unclear. Here, Dehinwal et al. show that acidic pH induces conformational changes in an outer membrane protein that affect its interaction with membrane lipids, thus modulating OMV formation.

    • Ruchika Dehinwal
    • Tata Gopinath
    • Francesca M. Marassi
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10
  • Determinants of Vibrio cholerae transmission are incompletely understood. Here, the authors use an infant mouse model to show that events in the intestine govern inter-animal transmission and that bacterial motility along with cholera toxin-driven diarrhea are critical for pathogen spread.

    • Ian W. Campbell
    • Ruchika Dehinwal
    • Matthew K. Waldor
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14