Nature Search

The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour

In humans, copy-number variants of the CYFIP1 gene have been associated with autism spectrum disorders and schizophrenia. Here, the authors characterize Cyfip1-heterozygous mice, revealing that they display deficits in brain white matter structure and functional connectivity along with abnormal behaviours.

Nuria Domínguez-Iturza
Adrian C. Lo
Claudia Bagni
ResearchOpen Access01 Aug 2019
Nature Communications

Volume: 10, P: 1-13
TBP as a candidate gene for mental retardation in patients with subtelomeric 6q deletions

Liesbeth Rooms
Edwin Reyniers
R Frank Kooy
Research14 Jun 2006
European Journal of Human Genetics

Volume: 14, P: 1090-1096
Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS

Trovò and colleagues find that aging is accompanied by a decrease in the levels of the phosphoinositide PI(4,5)P₂, PLCγ activity and the PI(4,5)P₂-clustering molecule MARCKS in mouse hippocampal synaptic membranes. Moreover, increasing MARCKS levels in old mice corrects some of the synaptic plasticity and memory deficits associated with aging.

Laura Trovò
Tariq Ahmed
Carlos G Dotti
Research24 Feb 2013
Nature Neuroscience

Volume: 16, P: 449-455
Author Correction: Automated procedure to assess pup retrieval in laboratory mice

Carmen Winters
Wim Gorssen
Rudi D’Hooge
Amendments and CorrectionsOpen Access14 Feb 2022
Scientific Reports

Volume: 12, P: 1
Automated procedure to assess pup retrieval in laboratory mice

Carmen Winters
Wim Gorssen
Rudi D’Hooge
ResearchOpen Access31 Jan 2022
Scientific Reports

Volume: 12, P: 1-9
Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity

Amira Latif-Hernandez
Disha Shah
Rudi D’Hooge
ResearchOpen Access07 Nov 2016
Scientific Reports

Volume: 6, P: 1-14
Estimating genetics of body dimensions and activity levels in pigs using automated pose estimation

Wim Gorssen
Carmen Winters
Nadine Buys
ResearchOpen Access13 Sept 2022
Scientific Reports

Volume: 12, P: 1-12
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice

Ann Van der Jeugd
Arnaldo Parra-Damas
Carlos A. Saura
ResearchOpen Access24 Apr 2018
Scientific Reports

Volume: 8, P: 1-12
Testosterone boosts physical activity in male mice via dopaminergic pathways

Ferran Jardí
Michaël R. Laurent
Dirk Vanderschueren
ResearchOpen Access17 Jan 2018
Scientific Reports

Volume: 8, P: 1-14
Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APP^NL-F/NL-F knock-in mice

Disha Shah
Amira Latif-Hernandez
Annemie Van der Linden
ResearchOpen Access19 Apr 2018
Scientific Reports

Volume: 8, P: 1-11
Prevention and treatment strategies for contextual overgeneralization

Dieuwke Sevenster
Kim Haesen
Rudi D’Hooge
ResearchOpen Access05 Dec 2017
Scientific Reports

Volume: 7, P: 1-14
Improved Long-Term Memory via Enhancing cGMP-PKG Signaling Requires cAMP-PKA Signaling

Eva Bollen
Daniela Puzzo
Jos Prickaerts
Research12 May 2014
Neuropsychopharmacology

Volume: 39, P: 2497-2505

Search

Filter By:

Search

Quick links