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Showing 1–6 of 6 results
Advanced filters: Author: Ruitao Jin Clear advanced filters
  • The Kir potassium channels are known to operate and gate without a major conformational change. Here, the authors identify the permeation gate of Kir channels as a steric plug within the conduction pathway, describing how tightly associated anionic lipids pushing into fenestrations in the pore walls engage with the plug to operate the gate.

    • Ruitao Jin
    • Sitong He
    • Jacqueline M. Gulbis
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11
  • The molecular basis of OSCA/TMEM63 channel mechanosensitivity was investigated by determining 44 cryogenic electron microscopy structures of channels in different environments, expanding understanding of channel-mediated mechanotransduction and pore formation, with implications for two protein families.

    • Yaoyao Han
    • Zijing Zhou
    • Yixiao Zhang
    Research
    Nature
    Volume: 628, P: 910-918
  • The transition between conducting and non-conducting states of K+ channels has been explained by conformational changes at the intracellular entrance to the conduction pathway. Here authors demonstrate that control over K+ currents in Kir channels is not explained by the canonical pore-gating model, as conduction is not impaired by a constricted inner helix bundle.

    • Katrina A. Black
    • Sitong He
    • Jacqueline M. Gulbis
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13
  • High temperature thermal instability and low temperature kinetics sluggishness of electrolytes pose significant barriers towards wide-temperature sodium-ion batteries. Here, the authors report a temperature-adaptive electrolyte by regulating the dipole-dipole interactions at various temperatures.

    • Meilong Wang
    • Luming Yin
    • Jun Lu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10
  • A new donkey reference genome and comparisons with wild asses yields insights into the evolutionary history of donkey domestication and identifies a genetic variant that results in the non-Dun coat colours of domestic donkeys.

    • Changfa Wang
    • Haijing Li
    • Jifeng Zhong
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15