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Showing 1–4 of 4 results
Advanced filters: Author: Ruo-Xu Gu Clear advanced filters

  • Hehlert et al. report that the gating spring that pulls open mechanosensitive NOMPC channels is not their helical ankyrin tether, but instead an elastic hinge that suspends that tether on the channel gate.

    • Philip Hehlert
    • Thomas Effertz
    • Martin C. Göpfert
    Research
    Nature Neuroscience
    Volume: 28, P: 259-267

  • The hydrophobic gating is believed to function in various ion channels. Here, the authors use MD simulations to assess how dewetting of the channel pore modulates the function and conformational transition of the potassium channels.

    • Ruo-Xu Gu
    • Bert L. de Groot
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12

  • Potassium (K+) channels, such as MthK, are essentional for many biological processes, but how lipid-protein interactions regulate ion permeation of K+ channels remained unclear. Here authors conducted molecular dynamics simulations of MthK and observed different ion permeation rates of MthK in membranes with different properties.

    • Ruo-Xu Gu
    • Bert L. de Groot
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10