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Showing 1–3 of 3 results
Advanced filters: Author: Ruoya Ho Clear advanced filters

  • Enterobacteriaceae modify cellulose with lipid-derived pEtN groups to promote biofilm cohesion. Here, using structural and biochemical analyses, the authors provide further insights into the molecular interactions of BcsA, BcsG, BcsB, and BcsC facilitating pEtN modification and secretion of cellulose.

    • Preeti Verma
    • Ruoya Ho
    • Jochen Zimmer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • A cryo-electron microscopy analysis reveals how HAS selects its substrates, hydrolyses the first substrate to prime the synthesis reaction, opens a hyaluronan-conducting transmembrane channel, ensures alternating substrate polymerization and coordinates hyaluronan inside its transmembrane pore.

    • Finn P. Maloney
    • Jeremi Kuklewicz
    • Jochen Zimmer
    Research
    Nature
    Volume: 604, P: 195-201

  • A new cryo-EM structure of the ~1 MDa Escherichia coli cellulose synthase macrocomplex reveals how cellulose biosynthesis and phosphoethanolamine (pEtN) modification are coupled to promote host-tissue adhesion.

    • Justin F. Acheson
    • Ruoya Ho
    • Jochen Zimmer
    Research
    Nature Structural & Molecular Biology
    Volume: 28, P: 310-318