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Lockyer's columns of controversy in Nature

Publisher Alexander Macmillan chose Norman Lockyer as Nature's founding Editor in 1869. It was an inspired choice, but Lockyer's powerful personality courted controversy in the fledgling magazine. Ruth Barton investigates.

Ruth Barton
Research09 Oct 2007
Nature

P: 1-3
Statistical evidence in psychological networks

Psychometric network models have become increasingly popular in psychology and the social sciences. Huth et al. show that a large proportion of reported network findings are based on weak or inconclusive evidence inviting caution when interpreting results.

Karoline B. S. Huth
Jonas M. B. Haslbeck
Maarten Marsman
Research09 Oct 2025
Nature Human Behaviour

P: 1-14
SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder

Different types of SETBP1 variants cause variable developmental syndromes with only partial clinical and functional overlaps. Here, the authors report that SETBP1 variants outside the degron region impair DNA-binding, transcription, and neuronal differentiation capacity and morphologies.

Maggie M. K. Wong
Rosalie A. Kampen
Simon E. Fisher
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-23
α-Chain contacts in the polymerization of sickle haemoglobin

Ruth E. Benesch
Suzanna Yung
Rose G. Schneider
Research18 Mar 1976
Nature

Volume: 260, P: 219-221
The Greenlandification of Antarctica

Climate and ice sheet processes in Antarctica increasingly reflect those observed earlier in Greenland. Applying process insights from Greenland can improve projections of future Antarctic ice and climate behaviour.

Ruth Mottram
Nicolaj Hansen
Benjamin J. Wallis
Comments & Opinion03 Oct 2025
Nature Geoscience

Volume: 18, P: 928-930
Lockyer’s columns of controversy in Nature

Publisher Alexander Macmillan chose Norman Lockyer as Nature’s founding Editor in 1869. It was an inspired choice, but Lockyer’s powerful personality courted controversy in the fledgling magazine. Ruth Barton investigates.

Ruth Barton
Special Features10 Oct 2007
Nature
Reductions in commuting mobility correlate with geographic differences in SARS-CoV-2 prevalence in New York City

New York City is one of the areas most affected by the SARS-CoV-2 pandemic in the United States, and there has been large variation in rates of hospitalisation and death by city borough. Here, the authors show that boroughs with the largest reduction in daily commutes also had the lowest SARS-CoV-2 prevalence.

Stephen M. Kissler
Nishant Kishore
Yonatan H. Grad
ResearchOpen Access16 Sept 2020
Nature Communications

Volume: 11, P: 1-6
Impact of ocean stratification on submarine melting of a major Greenland outlet glacier

Fiammetta Straneo
Ruth Curry
Leigh Stearns
ResearchOpen Access11 Feb 2011
Nature Precedings

P: 1
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Auxotrophic vaccines for tuberculosis

Indira Guleria
Rachel Teitelbaum
Barry R. Bloom
Research01 Mar 1996
Nature Medicine

Volume: 2, P: 334-337
Delayed Implantation in the Stoat (Mustela mustela)

RUTH DEANESLY
Research27 Mar 1943
Nature

Volume: 151, P: 365-366
Impact of fjord dynamics and glacial runoff on the circulation near Helheim Glacier

Submarine melting has been suggested as a trigger for the widespread acceleration of tidewater glaciers in Greenland. An analysis of oceanographic data from the fjord off Helheim Glacier, Greenland, suggests the presence of light Arctic and dense Atlantic waters in the fjord and that the melting circulation is more complex than thought.

Fiammetta Straneo
Ruth G. Curry
Leigh A. Stearns
Research20 Mar 2011
Nature Geoscience

Volume: 4, P: 322-327
Extraction of the Higher Fatty Acids from Human Malignant Tumours

ERIC PONDER
RUTH V. PONDER
Research31 Mar 1962
Nature

Volume: 193, P: 1300-1301
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Human outbreaks of a novel reassortant Oropouche virus in the Brazilian Amazon region

Genomic and epidemiologic analyses revealed that a novel reassortant viral lineage of the Oropouche virus, which has been circulating in the western Amazon region of Brazil for about a decade, is associated with the recent human outbreaks between 2022 and 2024.

Felipe Gomes Naveca
Tatiana Amaral Pires de Almeida
Gonzalo Bello
Research18 Sept 2024
Nature Medicine

Volume: 30, P: 3509-3521
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Cord Plasma Vasopressin, Erythropoietin, and Hypoxanthine as Indices of Asphyxia at Birth

Vineta Ruth
Frej Fyhrquist
Kari O Raivio
Research01 Oct 1988
Pediatric Research

Volume: 24, P: 490-494
Effect of Instantaneous Flashes on Adaptation of the Eye: Effects of Brilliant Flashes on Light and Dark Adaptation

JOHN E. DOWLING
RUTH HUBBARD
Research07 Sept 1963
Nature

Volume: 199, P: 972-975
A New Blood-Group Antibody, Anti-Jk^b

GERTRUDE PLAUT
ELIZABETH W. IKIN
R. R. RACE
Research07 Mar 1953
Nature

Volume: 171, P: 431
Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population

The factors influencing risk of reinfection with SARS-CoV-2 are poorly understood. Here, the authors use data from the UK COVID-19 Infection Survey, a community based longitudinal study, to assess characteristics of ~45,000 reinfections compared to initial infections.

Jia Wei
Nicole Stoesser
Chris Cunningham
ResearchOpen Access02 Feb 2024
Nature Communications

Volume: 15, P: 1-14
An Inherited Abnormality in Rhode Island Red Poultry

RUTH C. BAMBER
Research21 May 1932
Nature

Volume: 129, P: 762
Whole-genome sequencing of 490,640 UK Biobank participants

A study reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation.

Keren Carss
Bjarni V. Halldorsson
Ole Schulz-Trieglaff
ResearchOpen Access06 Aug 2025
Nature

Volume: 645, P: 692-701
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
Inflammatory diseases and risk of lung cancer among individuals who have never smoked

Inflammatory diseases may play an important role in lung cancer in never-smokers (LCINS) pathogenesis. Here, the authors show that conditions such as GERD or COPD could be considered as part of eligibility criteria for LCINS screening programs in the future.

Monica E. D’Arcy
Ruth M. Pfeiffer
Maria Teresa Landi
ResearchOpen Access02 Jun 2025
Nature Communications

Volume: 16, P: 1-12
Cytoplasmic Inclusions of Opalina and Nyctotherus

RUTH PATTEN
Research27 Aug 1932
Nature

Volume: 130, P: 311-312
Two distinct host-specialized fungal species cause white-nose disease in bats

The identification of two cryptic species of the fungal pathogen that causes white-nose disease in bats highlights the need to integrate studies of genetic variability in pathogens into disease surveillance, management and prevention strategies.

Nicola M. Fischer
Imogen Dumville
Sebastien J. Puechmaille
ResearchOpen Access28 May 2025
Nature

Volume: 642, P: 1034-1040
RANKL blockade for erosive hand osteoarthritis: a randomized placebo-controlled phase 2a trial

Denosumab, a receptor activator of nuclear factor-κB ligand inhibitor, previously developed for osteoporosis, was shown to be effective at inducing structural modification in patients with erosive hand osteoarthritis after 24 weeks.

Ruth Wittoek
Gust Verbruggen
Dirk Elewaut
ResearchOpen Access15 Feb 2024
Nature Medicine

Volume: 30, P: 829-836
Xg^a Investigations of the Family of a Child with a Ring X Chromosome

RUTH SANGER
R. R. RACE
Research14 Aug 1965
Nature

Volume: 207, P: 768
Mycorrhiza and Litter Decomposition

RUTH L. GADGIL
P. D. GADGIL
Research10 Sept 1971
Nature

Volume: 233, P: 133
Blood Group Antigens Mi^a and Vw and their Relation to the MNSs System

J. WALLACE
G. R. MILNE
R. R. RACE
Research02 Mar 1957
Nature

Volume: 179, P: 478
Interfertility Phenomena of the American and European Forms of Panus stypticus (Bull.) Fries

RUTH MACRAE
Research17 Apr 1937
Nature

Volume: 139, P: 674
Action of Mepacrine on Diamine Oxidase

H. BLASCHKO
RUTH DUTHIE
Research28 Jul 1945
Nature

Volume: 156, P: 113
Chicken and egg

Ruth A. Reck
Research09 Mar 1995
Nature

Volume: 374, P: 126
The Floating Barnacle on the North Cornish Coast in the Summer of 1933

J. H. ORTON
RUTH RAWLINSON
Research17 Mar 1934
Nature

Volume: 133, P: 418
Effects of Kinetin on Cell Division in Paramecium caudatum

RUTH GUTTMAN
AVIGDOR BACK
Research22 Mar 1958
Nature

Volume: 181, P: 852
Cytolytic Effect of Homogenates of Mouse Adenocarcinomas on White Cells

ERIC PONDER
RUTH V. PONDER
Research31 Mar 1962
Nature

Volume: 193, P: 1300
Induction of Subcutaneous Nodules in Rabbits with the SE Polyoma Virus

BERNICE E. EDDY
SARAH E. STEWART
RALPH D. YOUNG
Research14 Mar 1959
Nature

Volume: 183, P: 766-767
Effect of High Oxygen Pressure on the Protective Action of Cystamine and 5-Hydroxytryptamine in Irradiated Rats

H. A. S. VAN DEN BRENK
RUTH MOORE
Research30 May 1959
Nature

Volume: 183, P: 1530-1531
A Requirement for 2-Thiouracil of 2-Thiouracil-grown Escherichia coli under Conditions of Ornithine Transcarbamylase Repression

ADA ZAMIR
RUTH BEN-ISHAI
Research18 Mar 1961
Nature

Volume: 189, P: 922-923
Separation of Polypeptides bound by Albumin in Human Plasma

ALBERT L. RUBIN
GLENN D. LUBASH
PETER F. DAVISON
Research09 Mar 1963
Nature

Volume: 197, P: 1009-1010
Antitranspirant Activity of the Methyl and Phenyl Esters of Abscisic Acid

RUTH J. JONES
T. A. MANSFIELD
Research04 Jun 1971
Nature

Volume: 231, P: 331-332
Dose-response Relations of Amphetamine–Barbiturate Mixtures

RUTH RUSHTON
HANNAH STEINBERG
Research09 Mar 1963
Nature

Volume: 197, P: 1017-1018
Inhibition of the transition of a 40S ribosome–Met-tRNA_i^Met complex to an 80S ribosome–Met-tRNA_i^Met complex by 7-methylguanosine-5′-phosphate

RUTH ROMAN
JOHN D. BROOKER
ABRAHAM MARCUS
Research25 Mar 1976
Nature

Volume: 260, P: 359-360
Active immunization and passive transfer of resistance against sporozoite-induced malaria in infant mice

Augustine U. Orjih
Alan H. Cochrane
Ruth S. Nussenzweig
Research28 May 1981
Nature

Volume: 291, P: 331-332
Dynamic symbioses reveal pathways to coral survival through prolonged heatwaves

Climate change and local anthropogenic stressors threaten the persistence of coral reefs. Here the authors track coral bleaching over the course of a heatwave and find that some colonies recovered from bleaching while high temperatures persisted, but only at sites lacking in other strong anthropogenic stressors.

Danielle C. Claar
Samuel Starko
Julia K. Baum
ResearchOpen Access08 Dec 2020
Nature Communications

Volume: 11, P: 1-10
Intracellular migration of nuclear proteins in Xenopus oocytes

EDDY M. DE ROBERTIS
RUTH F. LONGTHORNE
J. B. GURDON
Research16 Mar 1978
Nature

Volume: 272, P: 254-256
Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

Tumour evolution and heterogeneity in high grade serous ovarian cancer (HGSOC) remains poorly characterised. Here, the authors investigate the genomic landscape of HGSOC and reveal two distinct evolutionary trajectories associated with clinical outcomes.

Ailith Ewing
Alison Meynert
Colin A. Semple
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle

Spillover of the highly pathogenic avian influenza H5N1 virus to dairy cattle and the findings of a clinical, pathological and epidemiological investigation in nine affected farms are reported.

Leonardo C. Caserta
Elisha A. Frye
Diego G. Diel
ResearchOpen Access25 Jul 2024
Nature

Volume: 634, P: 669-676
Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

Health care workers (HCW) are a high-risk population for SARS-CoV-2 infection. Here, the authors determine seroprevalence against SARS-CoV-2 in HCWs of a large Spanish reference hospital and find a cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive rRT-PCR) of 11%.

Alberto L. Garcia-Basteiro
Gemma Moncunill
Carlota Dobaño
ResearchOpen Access08 Jul 2020
Nature Communications

Volume: 11, P: 1-9
Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories

Many SARS-CoV-2 infections may go undetected through conventional PCR or lateral flow tests. Here, the authors analyse the utility of analysing longitudinal nucleocapsid antibody trajectories to improve identification of prior SARS-CoV-2 infections using surveillance data from the UK.

Leslie R. Zwerwer
Tim E. A. Peto
Chris Cunningham
ResearchOpen Access14 May 2025
Nature Communications

Volume: 16, P: 1-13

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