It has been proposed that resistance to targeted therapies in non-small cell lung carcinoma (NSCLC) is due to a nonhomogeneous cell population. Here the authors analyse preclinical NSCLC models using single-cell RNA-seq and identify drug tolerant cell states and subpopulations, as well as associated genes.
- Alexandre F. Aissa
- Abul B. M. M. K. Islam
- Elizaveta V. Benevolenskaya
