Drivers of physiological aging are also linked to the etiology of chronic obstructive pulmonary disease (COPD), including inflammation and senescence, both influenced by nicotinamide adenine dinucleotide (NAD+) metabolism. Norheim et al. performed a randomized controlled trial in patients with COPD, testing whether boosting NAD+ levels reduces airway inflammation.
- Kristoffer L. Norheim
- Michael Ben Ezra
- Morten Scheibye-Knudsen
