The crystal structure of an influenza antibody that recognizes a small, conserved site in the variable receptor-binding domain of HA is described; this antibody shows broad neutralization across multiple subtypes of influenza A virus through an antibody–antigen interaction dominated by a single heavy-chain complementarity-determining region 3 loop.
- Damian C. Ekiert
- Arun K. Kashyap
- Ian A. Wilson