Here the authors map drug-induced cis-regulatory elements by quantitative profiling of messenger and enhancer RNAs with CAGE. Enhancers of UGT1A1, TSKU, and CYP24A1, along with alleles affecting their regulatory activities, are revealed, shedding light on the genomic basis of adverse drug reactions.
- Saki Gotoh-Saito
- Ryoko Wada
- Hideya Kawaji
