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Showing 1–2 of 2 results
Advanced filters: Author: Ryota Ouda Clear advanced filters

  • The presentation of viral antigens to T cells via the MHC molecules is a critical component of the host response to viral infection. Here the authors suggest SARS-CoV-2 possesses the immune evasion strategy against the MHC class I pathway by targeting key transcriptional regulators.

    • Ji-Seung Yoo
    • Michihito Sasaki
    • Koichi S. Kobayashi
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17

  • Type I interferon signaling is critical for the control of infection. Here the authors show that zinc finger RNA-binding protein (ZFR) can control type I interferon responses, and that this control is itself regulated by distinct ZFR truncation patterns that differ between monocytes and macrophages.

    • Nazmul Haque
    • Ryota Ouda
    • J. Robert Hogg
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13