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Showing 1–50 of 158 results

Advanced filters: Author: S Cimino Clear advanced filters

A trithorax–like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

Malek Djabali
Licia Selleri
Glen A. Evans
Research01 Oct 1992
Nature Genetics

Volume: 2, P: 113-118
Potential role for wild-type p53 in leukemias with MLL gene translocations

Maureen D Megonigal
Eric F Rappaport
Carolyn A Felix
Research19 Mar 1998
Oncogene

Volume: 16, P: 1351-1356
KAT5 regulates neurodevelopmental states associated with G0-like populations in glioblastoma

Quiescent populations are a likely key source of treatment resistance in glioblastoma. Here, the authors characterize KAT5 as a critical mediator of quiescence and adoption of progenitor-like states.

Anca B. Mihalas
Sonali Arora
Patrick J. Paddison
ResearchOpen Access09 May 2025
Nature Communications

Volume: 16, P: 1-20
Projected asymmetric response of Adélie penguins to Antarctic climate change

Megan A. Cimino
Heather J. Lynch
Matthew J. Oliver
ResearchOpen Access29 Jun 2016
Scientific Reports

Volume: 6, P: 1-9
Long-term haemodialysis in spinal cord injured patients

N D Vaziri
Research01 Apr 1984
Spinal Cord

Volume: 22, P: 110-114
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

Maximilian Zenk
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Tektites far and wide

M. SHYAM PRASAD
P. S. RAO
Research27 Sept 1990
Nature

Volume: 347, P: 340
The Elovich Equation in Chemisorption Kinetics

I. S. MCLINTOCK
Research01 Dec 1967
Nature

Volume: 216, P: 1204-1205
Poor response to neoadjuvant chemotherapy in metaplastic breast carcinoma

Willard Wong
Edi Brogi
Hannah Y. Wen
ResearchOpen Access22 Jul 2021
npj Breast Cancer

Volume: 7, P: 1-7
Genetics and environment in Hodgkin's disease

Despite the prevalence of Hodgkin's disease and non-Hodgkin's lymphoma, the specific causes are poorly understood. A recent study makes the strongest case to date for a genetic link.

Henry T. Lynch
Joseph N. Marcus
News & Views01 Apr 1995
Nature Medicine

Volume: 1, P: 298-300
Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets

This study analysed genetic data of soil-transmitted helminths from 27 countries, revealing diversity impacting molecular test accuracy and highlighting the need to adapt diagnostics for effective STH surveillance.

Marina Papaiakovou
Andrea Waeschenbach
Stephen R. Doyle
ResearchOpen Access10 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Assessing the success of marine ecosystem restoration using meta-analysis

This study evaluated the success of marine ecosystem restoration efforts through a descriptive statistical comparison, a formal meta-analysis conducted on 764 active restoration interventions, and by using a mixed model based on a spectrum of survival data reported in the reviewed literature.

R. Danovaro
J. Aronson
S. Fraschetti
ResearchOpen Access29 Mar 2025
Nature Communications

Volume: 16, P: 1-12
GDF15 linked to maternal risk of nausea and vomiting during pregnancy

Elevated circulating levels of GDF15 in pregnant women are associated with severe nausea and vomiting, and sensitivity to such symptoms during pregnancy is partly determined by prepregnancy levels of this hormone.

M. Fejzo
N. Rocha
S. O’Rahilly
ResearchOpen Access13 Dec 2023
Nature

Volume: 625, P: 760-767
Cytogenetic studies of infant acute lymphoblastic leukemia: poor prognosis of infants with t(4;11) – a report of the Children’s Cancer Group

NA Heerema
HN Sather
GH Reaman
Research14 May 1999
Leukemia

Volume: 13, P: 679-686
High frequency of fusion transcripts of exon 11 and exon 4/5 in AF-4 gene is observed in cord blood, as well as leukemic cells from infant leukemia patients with t(4;11)(q21;q23)

S Yamamoto
M Zaitsu
S Miyazaki
Research02 Sept 1998
Leukemia

Volume: 12, P: 1398-1403
Lack of ETV6 (TEL) gene rearrangements or p16^INK4A/p15^INK4B homozygous gene deletions in infant acute lymphoblastic leukemia

KW Maloney
JE Rubnitz
SP Hunger
Research01 Jul 1997
Leukemia

Volume: 11, P: 979-983
Monitoring of minimal residual leukemia in patients with MLL-AF9 positive acute myeloid leukemia by RT-PCR

G Mitterbauer
C Zimmer
C Mannhalter
Research07 Oct 1999
Leukemia

Volume: 13, P: 1519-1524
A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level

T Leis
R Repp
F Lampert
Research29 May 1998
Leukemia

Volume: 12, P: 758-763
Therapy-related adult acute lymphoblastic leukemia with t(4;11)(q21; q23): MLL rearrangement, p53 mutation and multilineage involvement

R Bigoni
A Cuneo
G Castoldi
Research14 May 1999
Leukemia

Volume: 13, P: 704-707
Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL

Martin Reichel
Esther Gillert
Rolf Marschalek
Research24 May 2001
Oncogene

Volume: 20, P: 2900-2907
Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain

Ghajar and colleagues report that astrocyte-deposited laminin-211 promotes the quiescence of disseminated tumor cells in the brain, in a manner dependent on the cytoplasmic sequestration of YAP by dystroglycan.

Jinxiang Dai
Patrick J. Cimino
Cyrus M. Ghajar
Research24 Dec 2021
Nature Cancer

Volume: 3, P: 25-42
In utero rearrangements in the trithorax-related oncogene in infant leukaemias

Anthony M. Ford
Susan A. Ridge
Mel Greaves
Research27 May 1993
Nature

Volume: 363, P: 358-360
Outpatient management of acute promyelocytic leukemia after consolidation chemotherapy

C Girmenia
R Latagliata
G Alimena
Research16 Apr 1999
Leukemia

Volume: 13, P: 514-517
Survival on maintenance dialysis in patients with chronic renal failure associated with paraplegia and quadriplegia

M K Mirahmadi
N D Vaziri
S Gordon
Research01 Feb 1982
Spinal Cord

Volume: 20, P: 43-47
Reversal of transplantation immunity by liver grafting

Naoshi Kamada
H.ff.S. Davies
Bruce Roser
Research27 Aug 1981
Nature

Volume: 292, P: 840-842
Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation

Martin Reichel
Esther Gillert
Rolf Marschalek
Research09 Dec 1998
Oncogene

Volume: 17, P: 3035-3044
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

A new study from the eMERGE consortium provides insights on the development of a pipeline for the generation and reporting of polygenic risk scores for ten diseases to diverse populations in a clinical setting.

Niall J. Lennon
Leah C. Kottyan
Eimear E. Kenny
ResearchOpen Access19 Feb 2024
Nature Medicine

Volume: 30, P: 480-487
Infant leukaemia after in utero exposure to radiation from Chernobyl

E. Petridou
D. Trichopoulos
F. Tzortzatou
Research25 Jul 1996
Nature

Volume: 382, P: 352-353
Vascular access in haemodialysis: strengthening the Achilles' heel

Dialysis vascular access continues to be both a 'lifeline' and an 'Achilles' heel' for patients on haemodialysis. In this Review, the authors address some of the problems associated with vascular access, including dialysis access stenosis and arteriovenous fistula (AVF) maturation failure. They discuss the role of monitoring and surveillance, describe process of care pathways intended to increase AVF rates and decrease catheter use, and discuss novel therapies designed to reduce vascular access dysfunction.

Miguel C. Riella
Prabir Roy-Chaudhury
Reviews16 Apr 2013
Nature Reviews Nephrology

Volume: 9, P: 348-357
Association between pathologic response and survival after neoadjuvant therapy in lung cancer

Analysis of the phase 3 CheckMate 816 trial shows that the depth of pathologic response as assessed by percent residual viable tumor is correlated with event-free survival following neoadjuvant immunotherapy plus chemotherapy, supporting pathologic response as a biomarker of survival.

Julie Stein Deutsch
Ashley Cimino-Mathews
Janis M. Taube
ResearchOpen Access30 Oct 2023
Nature Medicine

Volume: 30, P: 218-228
Federated learning enables big data for rare cancer boundary detection

Federated ML (FL) provides an alternative to train accurate and generalizable ML models, by only sharing numerical model updates. Here, the authors present the largest FL study to-date to generate an automatic tumor boundary detector for glioblastoma.

Sarthak Pati
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access05 Dec 2022
Nature Communications

Volume: 13, P: 1-17
Differential regulation of E2F1 apoptotic target genes in response to DNA damage

Natalia Pediconi
Alessandra Ianari
Massimo Levrero
Research19 May 2003
Nature Cell Biology

Volume: 5, P: 552-558
Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma

In a large, partially prospective cohort of patients with molecularly profiled and clinically annotated meningioma, the extent of surgical resection and radiotherapy (RT) response correlate with molecular classification, which can be used in a molecular model to predict clinical outcomes in response to RT.

Justin Z. Wang
Vikas Patil
Gelareh Zadeh
ResearchOpen Access21 Aug 2024
Nature Medicine

Volume: 30, P: 3173-3183
Hypoxia induces ROS-resistant memory upon reoxygenation in vivo promoting metastasis in part via MUC1-C

Hypoxia is associated with metastasis and mortality. Here, the authors show that intratumoral hypoxia is linked to oxidative stress driving both HIF and NF-kB signaling to sustain a ROS-resistant phenotype that drives metastasis partially via MUC1-C.

Inês Godet
Harsh H. Oza
Daniele M. Gilkes
ResearchOpen Access28 Sept 2024
Nature Communications

Volume: 15, P: 1-19
Overproduction of N-Acetylneuraminic Acid (Sialic Acid) by Sialuria Fibroblasts

George H Thomas
Linda W Reynolds
Carol S Miller
Research01 May 1985
Pediatric Research

Volume: 19, P: 451-455
HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus

Steuernagel and Lam et al. present HypoMap, an integrated reference atlas of the murine hypothalamus based on 384,925 hypothalamic cells from publicly available single-cell sequencing datasets.

Lukas Steuernagel
Brian Y. H. Lam
Jens C. Brüning
ResearchOpen Access20 Oct 2022
Nature Metabolism

Volume: 4, P: 1402-1419
SIX YEARS EXPERIENCE IN HOME HAEMODIALYSIS (HHD) OF CHILDREN

D Michalk
K Schärer
E Reichwald
Research01 Aug 1980
Pediatric Research

Volume: 14, P: 994
Impacts of marine heatwaves on top predator distributions are variable but predictable

This study examines the effect of four marine heatwaves in the Northeast Pacific on the distributions of 14 top predators, revealing a wide-array of predator responses both among and within heatwaves. Predator responses were highly predictable, demonstrating capacity for early warning systems of heatwave impacts, similar to weather forecasts.

Heather Welch
Matthew S. Savoca
Elliott L. Hazen
ResearchOpen Access05 Sept 2023
Nature Communications

Volume: 14, P: 1-10
Sequential molecular monitoring of chimerism in chronic myeloid leukemia patients receiving donor lymphocyte transfusion for relapse after bone marrow transplantation

MC Rapanotti
W Arcese
G Cimino
Research01 Apr 1997
Bone Marrow Transplantation

Volume: 19, P: 703-707
Comparison of cytogenetics, Southern blotting, and fluorescence in situ hybridization as methods for detecting MLL gene rearrangements in children with acute leukemia and with 11q23 abnormalities

S Mathew
FG Behm
SC Raimondi
Research03 Nov 1999
Leukemia

Volume: 13, P: 1713-1720
MC3R links nutritional state to childhood growth and the timing of puberty

MC3R deficiency is associated with a delay in the onset of puberty, and a reduction in growth and lean mass.

B. Y. H. Lam
A. Williamson
S. O’Rahilly
Research03 Nov 2021
Nature

Volume: 599, P: 436-441
Immunophenotype of adult and childhood acute lymphoblastic leukemia: changes at first relapse and clinico-prognostic implications

C Guglielmi
I Cordone
R Foa
Research01 Sept 1997
Leukemia

Volume: 11, P: 1501-1507
GDF15 mediates the effects of metformin on body weight and energy balance

In mouse studies, metformin treatment results in increased secretion of growth/differentiation factor 15 (GDF15), which prevents weight gain in response to high-fat diet, and GDF15-independent lowering of circulating blood glucose.

Anthony P. Coll
Michael Chen
Stephen O’Rahilly
Research25 Dec 2019
Nature

Volume: 578, P: 444-448
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways

Tropomyosin receptor kinase B (TrkB), encoded by the neurotrophic tyrosine receptor kinase 2 (NTRK2) gene, exhibits intricate splicing patterns and post-translational modifications. Here, the authors perform whole gene and transcript-level analyses and report the TrkB.T1 splice variant enhances PDGF-driven gliomas in vivo and augments PI3K signaling cascades in vitro.

Siobhan S. Pattwell
Sonali Arora
Eric C. Holland
ResearchOpen Access12 Jun 2020
Nature Communications

Volume: 11, P: 1-14
Nilotinib versus imatinib with early switch from imatinib to nilotinib to obtain treatment-free remission in newly diagnosed chronic myeloid leukemia patients: the analysis of the first co-primary endpoint

Fausto Castagnetti
Massimo Breccia
Fabrizio Pane
ResearchOpen Access18 Nov 2025
Leukemia

Volume: 40, P: 47-54
Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance

Anthony P. Coll
Michael Chen
Stephen O’Rahilly
Amendments and Corrections13 Feb 2020
Nature

Volume: 578, P: E24
Hematologic malignancies with t(4;11)(q21;q23) – a cytogenetic, morphologic, immunophenotypic and clinical study of 183 cases

B Johansson
AV Moorman
LM Secker-Walker
News29 May 1998
Leukemia

Volume: 12, P: 779-787
Ionized gas extends over 40 kpc in an odd radio circle host galaxy

We find that the optical emission due to ionized gas that is characteristic of a shock extends 40 kpc in diameter across the host galaxy of an odd radio circle.

Alison L. Coil
Serena Perrotta
Kelly E. Whalen
Research08 Jan 2024
Nature

Volume: 625, P: 459-462
Seasonal variations in the onset of childhood leukaemia and lymphoma

RMC Westerbeek
V Blair
JM Birch
Research01 Jul 1998
British Journal of Cancer

Volume: 78, P: 119-124
Alterations of p16 and p15 genes in acute leukemia with MLL gene rearrangements and their correlation with clinical features

H Ohnishi
SX Guo
Y Hayashi
Research01 Dec 1997
Leukemia

Volume: 11, P: 2120-2124

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