Cerium oxide nanoparticles (CeONPs) have attracted much attention because they possess multi-enzyme mimetic properties and have been used in bioanalysis, biomedicine, drug delivery, bioscaffold and so on. This review summarizes recent achievements on CeONPs catalytic mechanisms, the multi-enzyme-like activity, and their biomedical applications, such as in treatment of cancer, diabetes and Alzheimer’s disease.
