Nature Search

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Erratum: Opposing roles for p16^Ink4a and p19^Arf in senescence and ageing caused by BubR1 insufficiency

Darren J. Baker
Carmen Perez-Terzic
Jan M. van Deursen
Amendments and Corrections30 May 2012
Nature Cell Biology

Volume: 14, P: 649
Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1

Macrophages have been reported to regulate thermogenic, sympathetic neuron-mediated norepinephrine signaling in adipose tissues. Here the authors report that male mice lacking the allograft inflammatory factor-1 protein are resistant to diet-induced obesity, in association with higher adipose norepinephrine levels and lower expression of the norepinephrine catabolic enzyme monoamine oxidase A.

Prameladevi Chinnasamy
Isabel Casimiro
Nicholas E. S. Sibinga
ResearchOpen Access03 Jan 2023
Nature Communications

Volume: 14, P: 1-13
Spartan deficiency causes genomic instability and progeroid phenotypes

Spartan/DVC1 is a translesion synthesis regulator with important roles in cellular DNA damage tolerance. Here, the authors report that Spartan is essential for DNA lesion bypass and that Spartan insufficiency in mice causes chromosomal instability, cellular senescence and early onset of age-related phenotypes.

Reeja S. Maskey
Myoung Shin Kim
Yuichi J. Machida
ResearchOpen Access11 Dec 2014
Nature Communications

Volume: 5, P: 1-12
Improved NDVI based proxy leaf-fall indicator to assess rainfall sensitivity of deciduousness in the central Indian forests through remote sensing

Beependra Singh
C. Jeganathan
V. S. Rathore
ResearchOpen Access19 Oct 2020
Scientific Reports

Volume: 10, P: 1-16
Opposing roles for p16^Ink4a and p19^Arf in senescence and ageing caused by BubR1 insufficiency

Darren J. Baker
Carmen Perez-Terzic
Jan M. van Deursen
Research30 May 2008
Nature Cell Biology

Volume: 10, P: 825-836
Retinoic acid downregulates Rae1 leading to APC^Cdh1 activation and neuroblastoma SH-SY5Y differentiation

J Cuende
S Moreno
A Almeida
Research21 Jan 2008
Oncogene

Volume: 27, P: 3339-3344
B lymphocyte–directed immunotherapy promotes long-term islet allograft survival in nonhuman primates

Chengyang Liu
Hooman Noorchashm
Ali Naji
Research28 Oct 2007
Nature Medicine

Volume: 13, P: 1295-1298
Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

Philip E. Mosley
Johan N. van der Meer
Luca Cocchi
ResearchOpen Access27 Aug 2024
Molecular Psychiatry

Volume: 30, P: 848-860
BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD)

Y Niikura
H Ogi
K Kitagawa
Research08 Jan 2010
Cell Death & Differentiation

Volume: 17, P: 1011-1024
Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo

G Högnäs
S Tuomi
J Ivaska
ResearchOpen Access28 Nov 2011
Oncogene

Volume: 31, P: 3597-3606
Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis

P Nagarajan
T M Onami
S Venkatachalam
Research12 Jan 2009
Oncogene

Volume: 28, P: 1053-1062
Blended learning as an adjunct to tutor-led seminars in undergraduate orthodontics: a randomised controlled trial

Sri Jeganathan
Padhraig S. Fleming
Research13 Mar 2020
British Dental Journal

Volume: 228, P: 371-375
Long-term visual outcomes of intravitreal ranibizumab treatment for wet age-related macular degeneration and effect on blindness rates in south-east Scotland

S Borooah
V S Jeganathan
P Cackett
Research05 Jun 2015
Eye

Volume: 29, P: 1156-1161
Labeling of biotin antibodies with horseradish peroxidase using cyanuric chloride

Ramadan A Abuknesha
Fiona Jeganathan
Zakeya Baalawy
Protocols12 Mar 2009
Nature Protocols

Volume: 4, P: 452-460
Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity

Matthias P. Müller
Sadasivam Jeganathan
Roger S. Goody
ResearchOpen Access16 Jun 2017
Scientific Reports

Volume: 7, P: 1-11
Videoconferencing to deliver genetics services: a systematic review of telegenetics in light of the COVID-19 pandemic

Elizabeth G. Brown
Isabella Watts
Imran Rafi
Reviews06 Apr 2021
Genetics in Medicine

Volume: 23, P: 1438-1449
Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

Katie Pollock
Manjuan Liu
Sebastian Guettler
ResearchOpen Access13 Dec 2019
Scientific Reports

Volume: 9, P: 1-20
eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration

A Amiri
F Noei
J M Lee
Research20 Nov 2006
Oncogene

Volume: 26, P: 3027-3040
Caspr2-reactive antibody cloned from a mother of an ASD child mediates an ASD-like phenotype in mice

L Brimberg
S Mader
B Diamond
Research04 Oct 2016
Molecular Psychiatry

Volume: 21, P: 1663-1671

Search

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Erratum: Opposing roles for p16^Ink4a and p19^Arf in senescence and ageing caused by BubR1 insufficiency

Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1

Spartan deficiency causes genomic instability and progeroid phenotypes

Improved NDVI based proxy leaf-fall indicator to assess rainfall sensitivity of deciduousness in the central Indian forests through remote sensing

Opposing roles for p16^Ink4a and p19^Arf in senescence and ageing caused by BubR1 insufficiency

Retinoic acid downregulates Rae1 leading to APC^Cdh1 activation and neuroblastoma SH-SY5Y differentiation

B lymphocyte–directed immunotherapy promotes long-term islet allograft survival in nonhuman primates

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD)

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo

Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis

Blended learning as an adjunct to tutor-led seminars in undergraduate orthodontics: a randomised controlled trial

Long-term visual outcomes of intravitreal ranibizumab treatment for wet age-related macular degeneration and effect on blindness rates in south-east Scotland

Labeling of biotin antibodies with horseradish peroxidase using cyanuric chloride

Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity

Videoconferencing to deliver genetics services: a systematic review of telegenetics in light of the COVID-19 pandemic

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration

Caspr2-reactive antibody cloned from a mother of an ASD child mediates an ASD-like phenotype in mice

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