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Showing 301–350 of 406 results

Advanced filters: Author: S Mahoney Clear advanced filters

First-in-human phase I dose escalation trial of the first-in-class tumor microenvironment modulator VT1021 in advanced solid tumors

Mahalingam et al. report findings from a first-in-human dose escalation study of the tumor microenvironment modulator VT1021 in patients with advanced solid tumors. VT1021 is found to be safe and well tolerated and the recommended phase II dose is established based on pharmacokinetic/dynamic properties and preliminary clinical activities.

Devalingam Mahalingam
Wael Harb
Jing Watnick
ResearchOpen Access13 Jan 2024
Communications Medicine

Volume: 4, P: 1-12
Inhibition of casein kinase 1δ/εimproves cognitive-affective behavior and reduces amyloid load in the APP-PS1 mouse model of Alzheimer’s disease

S. Sundaram
S. Nagaraj
D. Gulick
ResearchOpen Access24 Sept 2019
Scientific Reports

Volume: 9, P: 1-13
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer’s disease

Emily R. Mahoney
Logan Dumitrescu
Timothy J. Hohman
ResearchOpen Access22 Jul 2019
Molecular Psychiatry

Volume: 26, P: 888-896
505 SEPARATION OF FETAL AND ADULT ERYTHROCYTES BY SELECTIVE HEMOLYSIS: AN AID TO PERNTAL DIAGNOSIS OF HEMOGLOBINOPATHIES

Blanche P Alter
David G Nathan
Bernard G Forget
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 448
VARIABLE SUPPRESSION OF IN VITRO GRANULOPOIESIS BY β-LACTAM ANTIBIOTICS

D H Mahoney Jr.
D Clark
S L Kaplan
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 244
Desmoglein-2 is important for islet function and β-cell survival

Kay K. Myo Min
Darling Rojas-Canales
Claudine S. Bonder
ResearchOpen Access29 Oct 2022
Cell Death & Disease

Volume: 13, P: 1-15
Inhibition of casein kinase 1 δ/ε improves cognitive performance in adult C57BL/6J mice

Heather Mahoney
Emily Peterson
Danielle Gulick
ResearchOpen Access26 Feb 2021
Scientific Reports

Volume: 11, P: 1-13
Far-UVC (222 nm) efficiently inactivates an airborne pathogen in a room-sized chamber

Ewan Eadie
Waseem Hiwar
Kenneth Wood
ResearchOpen Access23 Mar 2022
Scientific Reports

Volume: 12, P: 1-9
Speaking valve with integrated biomimetic overpressure release and acoustic warning signal

N. Knorr
P. Auth
T. Speck
ResearchOpen Access04 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

V M Whitehead
J J Shuster
B Camitta
Research17 Feb 2005
Leukemia

Volume: 19, P: 533-536
A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating combination chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group phase III randomized trial

SJ Lauer
JJ Shuster
BM Camitta
Research19 Jul 2001
Leukemia

Volume: 15, P: 1038-1045
A dual-reporter, diagnostic vector for prostate cancer detection and tumor imaging

J R Richter
M Mahoney
K R Zinn
Research24 Jul 2014
Gene Therapy

Volume: 21, P: 897-902
Effect of visual impairment upon oral health care: a review

E. K. Mahoney
N. Kumar
S. R. Porter
Research26 Jan 2008
British Dental Journal

Volume: 204, P: 63-67
LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition

C L Mahoney
B Choudhury
P A Futreal
ResearchOpen Access22 Jan 2009
British Journal of Cancer

Volume: 100, P: 370-375
Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype–phenotype correlation

Magdalena Koczkowska
Tom Callens
Ludwine M. Messiaen
ResearchOpen Access07 Sept 2018
Genetics in Medicine

Volume: 21, P: 867-876
1446 Monitoring Ventilation During Flight Retrieval of Critically Ill Children

S Mahoney
D Lutman
Research01 Nov 2010
Pediatric Research

Volume: 68, P: 714
A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children's Cancer Study Group Investigation

E J Estlin
C R Pinkerton
A D J Pearson
ResearchOpen Access03 Jan 2001
British Journal of Cancer

Volume: 84, P: 11-18
Prediction of high risk Ewing's sarcoma by gene expression profiling

Anat Ohali
Smadar Avigad
Isaac Yaniv
Research27 Sept 2004
Oncogene

Volume: 23, P: 8997-9006
The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

VM Whitehead
C Payment
B Camitta
Research19 Jul 2001
Leukemia

Volume: 15, P: 1081-1088
Maternal plasma DNA testing for aneuploidy in pregnancies achieved by assisted reproductive technologies

Geralyn Lambert-Messerlian
Edward M. Kloza
Glenn E. Palomaki
Research03 Oct 2013
Genetics in Medicine

Volume: 16, P: 419-422
Single cell RNA-seq study of wild type and Hox9,10,11 mutant developing uterus

Michael L. Mucenski
Robert Mahoney
S. Steven Potter
ResearchOpen Access14 Mar 2019
Scientific Reports

Volume: 9, P: 1-16
Additive manufacturing titanium components with isotropic or graded properties by hybrid electron beam melting/hot isostatic pressing powder processing

E. Hernández-Nava
P. Mahoney
S. Tammas-Williams
ResearchOpen Access11 Mar 2019
Scientific Reports

Volume: 9, P: 1-11
Candidate tumor-suppressor genes on chromosome arm 8p in early-onset and high-grade breast cancers

Jane E Armes
Fleur Hammet
Deon J Venter
Research07 Jun 2004
Oncogene

Volume: 23, P: 5697-5702
Re-evaluating the link between neuropsychiatric disorders and dysregulated adult neurogenesis

Recent evidence indicates that one of the underlying mechanisms in the pathogenesis of neuropsychiatric disorders is dysregulated dentate gyrus neurogenesis. Here the authors present evidence supporting this hypothesis and suggest therapeutic avenues.

Sanghee Yun
Ryan P Reynolds
Amelia J Eisch
Reviews26 Oct 2016
Nature Medicine

Volume: 22, P: 1239-1247
Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney

Keri A. Drake
Mike Adam
S. Steven Potter
ResearchOpen Access20 Apr 2018
Scientific Reports

Volume: 8, P: 1-14
Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study

J Pullen
JJ Shuster
B Camitta
Research03 Nov 1999
Leukemia

Volume: 13, P: 1696-1707
Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-x_L

S Wang
Z Wang
S Grant
Research07 Oct 1999
Leukemia

Volume: 13, P: 1564-1573
Allelic distribution of CTG18.1 in Caucasian populations: association studies in bipolar disorder, schizophrenia, and ataxia

M G McInnis
T Swift-Scanlanl
C A Ross
Research30 Jun 2000
Molecular Psychiatry

Volume: 5, P: 439-442
Surface antigen phenotype can predict TEL-AML1 rearrangement in childhood B-precursor ALL: a Pediatric Oncology Group study

MJ Borowitz
J Rubnitz
B Camitta
Research22 Oct 1998
Leukemia

Volume: 12, P: 1764-1770
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid

M Andreeff
S Jiang
S Zhao
Research03 Nov 1999
Leukemia

Volume: 13, P: 1881-1892
A multiplex RT-PCR assay for the detection of chimeric transcripts encoded by the risk-stratifying translocations of pediatric acute lymphoblastic leukemia

P Scurto
M Hsu Rocha
JR Downing
Research08 Dec 1998
Leukemia

Volume: 12, P: 1994-2005
Sex Differences in μ-Opioid Receptor Regulation of the Rat Locus Coeruleus and Their Cognitive Consequences

Herminio M Guajardo
Kevin Snyder
Rita J Valentino
ResearchOpen Access09 Nov 2016
Neuropsychopharmacology

Volume: 42, P: 1295-1304
Genetic studies of childhood acute lymphoblastic leukemia with emphasis on p16, MLL, and ETV6 gene abnormalities: results of St Jude Total Therapy Study XII

JE Rubnitz
FG Behm
JR Downing
Research01 Aug 1997
Leukemia

Volume: 11, P: 1201-1206
Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors

C Ferlini
M Distefano
G Scambia
ResearchOpen Access05 Dec 2000
British Journal of Cancer

Volume: 83, P: 1762-1768
The effects of exercise training on physical capacity, strength, body composition and functional performance among adults with spinal cord injury: a systematic review

A L Hicks
K A Martin Ginis
D L Wolfe
Research07 Jun 2011
Spinal Cord

Volume: 49, P: 1103-1127
Family History of Hypertension and Arterial Elasticity Characteristics in Healthy Young People

Lin Zhou
Yuanyuan Chen
Xirong Liu
Research01 May 2008
Hypertension Research

Volume: 31, P: 833-839
Desmoids in familial adenomatous polyposis are monoclonal proliferations

S B Middleton
I M Frayling
R K S Phillips
ResearchOpen Access20 Jan 2000
British Journal of Cancer

Volume: 82, P: 827-832
Minimal residual disease after intensive induction therapy in childhood acute lymphoblastic leukemia predicts outcome

B Gruhn
S Hongeng
GR Kitchingman
Research29 May 1998
Leukemia

Volume: 12, P: 675-681
Microsatellite-stable diploid carcinoma: a biologically distinct and aggressive subset of sporadic colorectal cancer

N J Hawkins
I Tomlinson
R L Ward
ResearchOpen Access16 Jan 2001
British Journal of Cancer

Volume: 84, P: 232-236
TGF-β1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells

S B Pakala
K Singh
R Kumar
Research24 Jan 2011
Oncogene

Volume: 30, P: 2230-2241
Alcohol, smoking, passive smoking and caffeine in relation to breast cancer risk in young women

SJ Smith
JM Deacon
CED Chilvers
Research01 Jul 1994
British Journal of Cancer

Volume: 70, P: 112-119
Energy expenditure and physical fitness in overweight vs non-overweight prepubertal girls

MS Treuth
R Figueroa-Colon
MI Goran
Research15 May 1998
International Journal of Obesity

Volume: 22, P: 440-447
Effect of P-glycoprotein on flavopiridol sensitivity

S A Boerner
M E Tourne
K C Bible
ResearchOpen Access15 May 2001
British Journal of Cancer

Volume: 84, P: 1391-1396
Death from early colorectal cancer is predicted by the presence of transcripts of the REG gene family

R C A Macadam
A I Sarela
P J Guillou
ResearchOpen Access20 Jun 2000
British Journal of Cancer

Volume: 83, P: 188-195
Dynamics of global disclosure through patent and journal publications for biopharmaceutical products

Examining the relationships between invention disclosure type in industry and academia and geographical disclosure trends, using plant-made pharmaceuticals as a single-sector model for the biopharmaceutical industry.

Harry Thangaraj
Craig J van Dolleweerd
Julian K-C Ma
Comments & Opinion01 Jul 2009
Nature Biotechnology

Volume: 27, P: 614-618
Developmental Gene Expression in the Human Fetal Pancreas

Martin I Mally
Timo Otonkoski
Alberto Hayek
Research01 Oct 1994
Pediatric Research

Volume: 36, P: 537-544
Lipid, lipoprotein and apolipoprotein profiles in European adolescents and its associations with gender, biological maturity and body fat—The HELENA Study

A Spinneker
S Egert
P Stehle
Research18 Jan 2012
European Journal of Clinical Nutrition

Volume: 66, P: 727-735
WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ

S W Chan
C J Lim
W Hong
ResearchOpen Access25 Oct 2010
Oncogene

Volume: 30, P: 600-610
cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation

S McComb
H H Cheung
S Sad
Research11 May 2012
Cell Death & Differentiation

Volume: 19, P: 1791-1801
Inhibitory effects of the combination of HER-2 antisense oligonucleotide and chemotherapeutic agents used for the treatment of human breast cancer

Antonina S Rait
Kathleen F Pirollo
Esther H Chang
Research30 Oct 2001
Cancer Gene Therapy

Volume: 8, P: 728-739

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