The pedunculopontine nucleus (PPN) is a target for deep brain stimulation for the control of gait and postural disability, but its role in gait control is not understood. Here, using extracellular single-unit recordings in awake patients, the authors show that neurons in the PPN respond to limb movement and imagined gait by dynamically changing network activity and decreasing alpha phase locking.
- Timothy L Tattersall
- Peter G Stratton
- Pankaj Sah
