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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Multi-ancestry meta-analyses of genome-wide association studies for self-reported physical activity during leisure time, leisure screen time, sedentary commuting and sedentary behavior at work identify 99 loci associated with at least one of these traits.

Zhe Wang
Andrew Emmerich
Marcel den Hoed
ResearchOpen Access07 Sept 2022
Nature Genetics

Volume: 54, P: 1332-1344
Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study

Shanice Christie
Sébastien Robiou-du-Pont
David Meyre
ResearchOpen Access06 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Expressed fusion gene landscape and its impact in multiple myeloma

Multiple myeloma is a malignancy of plasma cells in the blood. Here, the authors establish the landscape of fusion genes within this disease, identifying novel recurrent fusion genes that impact survival and may drive disease progression.

A. Cleynen
R. Szalat
H. Avet-Loiseau
ResearchOpen Access01 Dec 2017
Nature Communications

Volume: 8, P: 1-10
Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population

S Robiou-du-Pont
A Bonnefond
D Meyre
Research23 Oct 2012
International Journal of Obesity

Volume: 37, P: 980-985
Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study

Hudson Reddon
Hertzel C. Gerstein
David Meyre
ResearchOpen Access04 Jan 2016
Scientific Reports

Volume: 6, P: 1-10
Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology

Adeola F. Ishola
Hertzel C. Gerstein
David Meyre
ResearchOpen Access02 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
Lack of association between type 2 diabetes and major depression: epidemiologic and genetic evidence in a multiethnic population

Z Samaan
S Garasia
D Meyre
ResearchOpen Access11 Aug 2015
Translational Psychiatry

Volume: 5, P: e618

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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study

Expressed fusion gene landscape and its impact in multiple myeloma

Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population

Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study

Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology

Lack of association between type 2 diabetes and major depression: epidemiologic and genetic evidence in a multiethnic population

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