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Showing 1–3 of 3 results
Advanced filters: Author: Sainath Mamde Clear advanced filters

  • An atlas of candidate cis-regulatory DNA elements (cCREs) in the adult mouse brain unravels the transcriptional regulatory programs that drive the heterogeneity and complexity of brain structure and function.

    • Songpeng Zu
    • Yang Eric Li
    • Bing Ren
    ResearchOpen Access
    Nature
    Volume: 624, P: 378-389

  • TRIM28 depletion in embryonic stem cells disconnects transcriptional condensates from super-enhancers, which is rescued by knockdown of endogenous retroviruses.

    • Vahid Asimi
    • Abhishek Sampath Kumar
    • Denes Hnisz
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 1238-1247

  • Microglia, the innate immune cells of the brain, exhibit diverse functions and can influence Alzheimer’s disease progression. This study explores human microglial diversity in Alzheimer’s disease, uncovering unique disease-associated microglial populations and predicting underlying gene regulatory networks.

    • Katherine E. Prater
    • Kevin J. Green
    • Suman Jayadev
    ResearchOpen Access
    Nature Aging
    Volume: 3, P: 894-907