Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Advertisement

Nature

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Scientific Reports (40)
Nature Communications (9)
Oncogene (4)
Communications Biology (4)
Hypertension Research (3)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (72)
Amendments and Corrections (2)

Subject Check one or more subjects to show results from those subjects only.

Anatomy
Biomarkers
Cancer
Cell biology
Computational biology and bioinformatics
Developmental biology
Diseases
Ecology
Engineering
Genetics
Health care
Immunology
Medical research
Microbiology
Neurology
Neuroscience
Pathogenesis
Rheumatology
Risk factors
Signs and symptoms

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–50 of 74 results

Advanced filters: Author: Sakae Tanaka Clear advanced filters

Structures of the troponin C regulatory domains in the apo and calcium-saturated states

Stéphane M. Gagné
Sakae Tsuda
Brian D. Sykes
Research01 Sept 1995
Nature Structural Biology

Volume: 2, P: 784-789
c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption

Sakae Tanaka
Michael Amling
Roland Baron
Research10 Oct 1996
Nature

Volume: 383, P: 528-531
Characterization of Mycobacterium antarcticum sp. nov., a psychrotolerant member of the genus Mycobacterium isolated from Antarctic soil

Sho Shimada
Kotaro Aoki
Kazuhiro Tateda
ResearchOpen Access01 Oct 2025
Scientific Reports

Volume: 15, P: 1-12
New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide

Sakae Tanaka
Taiji Adachi
John P Bilezikian
ResearchOpen Access16 Dec 2014
Bone Research

Volume: 2, P: 1-7
Factors associated with cam deformity in Japanese local residents

Koichi Tomomatsu
Takaya Taniguchi
Hiroshi Yamada
ResearchOpen Access18 Jan 2024
Scientific Reports

Volume: 14, P: 1-7
Multiple insular-prefrontal pathways underlie perception to execution during response inhibition in humans

Osada et al. used MRI and brain stimulation to outline the macroscopic cerebral circuits for response inhibition: visual cortex→dorsal anterior insula→inferior frontal cortex→basal ganglia/motor cortex, confirming the insula’s critical bridging role.

Takahiro Osada
Koji Nakajima
Seiki Konishi
ResearchOpen Access03 Dec 2024
Nature Communications

Volume: 15, P: 1-17
Association between acetabular dysplasia and sagittal spino-pelvic alignment in a population-based cohort in Japan

Teiji Harada
Hiroshi Hashizume
Hiroshi Yamada
ResearchOpen Access25 Jul 2022
Scientific Reports

Volume: 12, P: 1-7
Relationship of sagittal spinal alignment with low back pain and physical performance in the general population

Kazuhiro Hira
Keiji Nagata
Hiroshi Yamada
ResearchOpen Access18 Oct 2021
Scientific Reports

Volume: 11, P: 1-8
ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts

Osteoclastic bone destruction is mediated by factors such as RANKL elaborated by tissue-destructive fibroblasts. Takayanagi and colleagues identify the transcription factor Ets1 as a major regulator of these pathogenic cells.

Minglu Yan
Noriko Komatsu
Hiroshi Takayanagi
Research23 Aug 2022
Nature Immunology

Volume: 23, P: 1330-1341
Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans

Vertically oscillating head motions mimicking mechanical accelerations experienced during light jogging or treadmill running at moderate velocity reduce blood pressure in rats and human adults with hypertension.

Shuhei Murase
Naoyoshi Sakitani
Yasuhiro Sawada
ResearchOpen Access06 Jul 2023
Nature Biomedical Engineering

Volume: 7, P: 1350-1373
CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade

TAK-931 is a selective CDC7 inhibitor and can induce replication stress (RS)-mediated chromosomal instability with antitumoral activity. Here the authors show that TAK-931-induced RS generates aneuploid cells with an inflammatory phenotype, rendering tumors sensitive to immune-checkpoint blockade.

Tomoko Yamamori Morita
Jie Yu
Akihiro Ohashi
ResearchOpen Access18 Nov 2023
Nature Communications

Volume: 14, P: 1-21
Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development

Possible distinct contributions of Runx 2 and Runx3 in osteoarthritis have not been clarified. Nagata et al. show that Runx3 protects adult articular cartilage by extracellular matrix protein production in normal conditions, while Runx2 exerts both catabolic and anabolic effects during inflammation.

Kosei Nagata
Hironori Hojo
Taku Saito
ResearchOpen Access19 Oct 2022
Nature Communications

Volume: 13, P: 1-17
Utility of Oblique Sagittal Reformatted and Three-dimensional Surface Reconstruction Computed Tomography in Foraminal Stenosis Decompression

Masahito Oshina
Yasushi Oshima
K. Daniel Riew
ResearchOpen Access30 Oct 2018
Scientific Reports

Volume: 8, P: 1-6
YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

The precise mechanisms of neuronal cell death in neurodegeneration are not fully understood. Here the authors show that YAP-mediated neuronal necrosis is increased in pre-symptomatic stages of Alzheimer’s disease and intervention to the necrosis rescues extracellular Aβ aggregation and symptoms in a mouse model.

Hikari Tanaka
Hidenori Homma
Hitoshi Okazawa
ResearchOpen Access24 Jan 2020
Nature Communications

Volume: 11, P: 1-22
Impact of lumbar spine pathology on asymmetrical hallux valgus in a population-based cohort study

Takumi Matsumoto
Ryutaro Takeda
Noriko Yoshimura
ResearchOpen Access30 Aug 2024
Scientific Reports

Volume: 14, P: 1-8
Author Correction: Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans

Shuhei Murase
Naoyoshi Sakitani
Yasuhiro Sawada
Amendments and CorrectionsOpen Access07 Nov 2023
Nature Biomedical Engineering

Volume: 7, P: 1530
Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway

Excessive mechanical stress promotes the development of osteoarthritis. Here Chang et al. identify gremlin-1 as a factor expressed in chondrocytes in response to mechanical stress, and contributing to osteoarthritis via activation of the NF-κB pathway.

Song Ho Chang
Daisuke Mori
Taku Saito
ResearchOpen Access29 Mar 2019
Nature Communications

Volume: 10, P: 1-13
Integrated genetic and epigenetic analysis of myxofibrosarcoma

Myxofibrosarcoma occurs in adults and is associated with high local relapse. Here, based on exome/transcriptome sequencing and DNA methylation analysis, the authors identify driver genes and methylation clusters associated with unique combinations of mutations, outcomes, and immune cell compositions.

Koichi Ogura
Fumie Hosoda
Tatsuhiro Shibata
ResearchOpen Access17 Jul 2018
Nature Communications

Volume: 9, P: 1-11
High-throughput functional evaluation of BRCA2 variants of unknown significance

Many germline variants are found in the BRCA2 gene, some of which pre-dispose women to breast and ovarian cancer. Here, the authors develop a method to determine the functional significance of BRCA2 variants and show that it is comparable to the IARC system of classifying variants.

Masachika Ikegami
Shinji Kohsaka
Hiroyuki Mano
ResearchOpen Access22 May 2020
Nature Communications

Volume: 11, P: 1-13
Effect of diabetes on patient-reported outcome measures at one year after laminoplasty for cervical spondylotic myelopathy

Kosei Nagata
Junya Miyahara
Yasushi Oshima
ResearchOpen Access11 Jun 2022
Scientific Reports

Volume: 12, P: 1-7
Prevalence and associated factors of pistol grip deformity in Japanese local residents

Takaya Taniguchi
Teiji Harada
Noriko Yoshimura
ResearchOpen Access16 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
Characteristics of the spinopelvic parameters of patients with sacroiliac joint pain

Juichi Tonosu
Hiroyuki Oka
Ko Matsudaira
ResearchOpen Access04 Mar 2021
Scientific Reports

Volume: 11, P: 1-5
Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum

Voltage-gated Na+ channel β-subunits are concentrated in the nodes of Ranvier and axon initial segments of myelinated axons and have a variety of functions. Here the authors show, using genetically modified mice, that this subunit is present in unmyelinated fibres in the striatum and is required for generation of resurgent Na+ current in striatal neurons.

Haruko Miyazaki
Fumitaka Oyama
Nobuyuki Nukina
Research21 Nov 2014
Nature Communications

Volume: 5, P: 1-15
Cruciate ligament force of knees following mobile-bearing unicompartmental knee arthroplasty is larger than the preoperative value

Kenichi Kono
Hiroshi Inui
Sakae Tanaka
ResearchOpen Access14 Sept 2021
Scientific Reports

Volume: 11, P: 1-9
In vivo kinematics and cruciate ligament forces in bicruciate-retaining total knee arthroplasty

Kenichi Kono
Hiroshi Inui
Darryl D. D’Lima
ResearchOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1-10
Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation

Fumiko Yano
Shinsuke Ohba
Ung-il Chung
ResearchOpen Access21 May 2019
Scientific Reports

Volume: 9, P: 1-9
Association between ossification of the longitudinal ligament of the cervical spine and arteriosclerosis in the carotid artery

Yasushi Oshima
Toru Doi
Sakae Tanaka
ResearchOpen Access25 Feb 2020
Scientific Reports

Volume: 10, P: 1-5
Prevalence of cervical anterior and posterior spondylolisthesis and its association with degenerative cervical myelopathy in a general population

Kimihide Murakami
Keiji Nagata
Hiroshi Yamada
ResearchOpen Access26 Jun 2020
Scientific Reports

Volume: 10, P: 1-8
Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis

Yasutaka Murahashi
Fumiko Yano
Taku Saito
ResearchOpen Access07 Nov 2018
Scientific Reports

Volume: 8, P: 1-8
Clinical and radiographic analysis of unilateral versus bilateral instrumented one-level lateral lumbar interbody fusion

Masayoshi Fukushima
Yasushi Oshima
Hirohiko Inanami
ResearchOpen Access20 Feb 2020
Scientific Reports

Volume: 10, P: 1-7
A simple method for sequencing the whole human mitochondrial genome directly from samples and its application to genetic testing

Yue Yao
Motoi Nishimura
Tomoaki Tanaka
ResearchOpen Access22 Nov 2019
Scientific Reports

Volume: 9, P: 1-7
Quantitative and qualitative characterization of expanded CD4⁺ T cell clones in rheumatoid arthritis patients

Kazuyoshi Ishigaki
Hirofumi Shoda
Kazuhiko Yamamoto
ResearchOpen Access06 Aug 2015
Scientific Reports

Volume: 5, P: 1-9
Pathogenic conversion of Foxp3⁺ T cells into T_H17 cells in autoimmune arthritis

Regulatory T (T_reg) cells exhibit substantial phenotypic and functional plasticity. Hiroshi Takayanagi and his colleagues report that in autoimmune arthritis, a subset of T_reg cells can lose Foxp3 expression and convert into T_H17 cells. This conversion is mediated by synovial fibroblast-derived IL-6, and in vivo, these cells are osteoclastogenic and exacerbate arthritis. These findings suggest that a proportion of pathogenic T_H17 cells in autoimmune disease may be derived from T_reg cells.

Noriko Komatsu
Kazuo Okamoto
Hiroshi Takayanagi
Research22 Dec 2013
Nature Medicine

Volume: 20, P: 62-68
Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes

Rela is a transcription factor shown to have seemingly contradictory roles in anabolism and catabolism of cartilage. Here the authors find that Rela prevents chondrocyte apoptosis and that homozygous knockout causes accelerated osteoarthritis in adults, whereas heterozygous knockout suppresses osteoarthritis by maintaining wild-type effects on apoptosis but inhibiting catabolic gene expression.

Hiroshi Kobayashi
Song Ho Chang
Taku Saito
ResearchOpen Access10 Nov 2016
Nature Communications

Volume: 7, P: 1-12
Complete sequencing and characterization of 21,243 full-length human cDNAs

Toshio Ota
Yutaka Suzuki
Sumio Sugano
Research21 Dec 2003
Nature Genetics

Volume: 36, P: 40-45
Highly Asymmetric-selective and Stereoselective Polymerization of (RS)-α-Methylbenzyl Methacrylate with Cyclohexyl-magnesium Bromide-Axially Dissymmetric 2,2′-Diamino-6,6′-dimethylbiphenyl System

Shigeyoshi Kanoh
Sakae Goka
Hiroshi Suda
Research01 Sept 1987
Polymer Journal

Volume: 19, P: 1047-1065
Acute exacerbation predicting poor outcomes in idiopathic interstitial pneumonia and advanced lung cancer patients undergoing cytotoxic chemotherapy

Atsushi Miyamoto
Hirofumi Michimae
I. Honda
ResearchOpen Access03 May 2024
Scientific Reports

Volume: 14, P: 1-14
Comparison between sacubitril/valsartan and thiazide diuretics among patients with uncontrolled hypertension in Japan

Kazuo Kobayashi
Mari Sotozawa
Akira Kanamori
Research19 May 2025
Hypertension Research

Volume: 48, P: 2058-2071
dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project

Soichi Ogishima
Satoshi Nagaie
Masayuki Yamamoto
ResearchOpen Access10 Dec 2021
Human Genome Variation

Volume: 8, P: 1-8
Osteoporosis, spinal degenerative disorders, and their association with low back pain, activities of daily living, and physical performance in a general population

Shoei Iwata
Hiroshi Hashizume
Hiroshi Yamada
ResearchOpen Access09 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis

Yoshinari Miyamoto
Akihiko Mabuchi
Shiro Ikegawa
Research25 Mar 2007
Nature Genetics

Volume: 39, P: 529-533
Single-polyp metabolomics for coral health assessment

Akira Iguchi
Mariko Iijima
Kei Zaitsu
ResearchOpen Access05 Mar 2024
Scientific Reports

Volume: 14, P: 1-7
Profiling of runs of homozygosity from whole-genome sequence data in Japanese biobank

Aye Ko Ko Minn
Motomichi Matsuzaki
Gen Tamiya
ResearchOpen Access03 Apr 2025
Journal of Human Genetics

Volume: 70, P: 287-296
Short-term overloading exercise attenuates articular chondrocyte features partly via synovium–cartilage interactions mediated by inhibin subunit beta A

Yusuke Arino
Asuka Terashima
Taku Saito
ResearchOpen Access25 Feb 2025
Scientific Reports

Volume: 15, P: 1-15
LTK mutations responsible for resistance to lorlatinib in non-small cell lung cancer harboring CLIP1-LTK fusion

A novel strategy using gilteritinib can overcome resistance to lorlatinib in non-small cell lung cancer with CLIP1-LTK-L650F mutation.

Shunta Mori
Hiroki Izumi
Susumu S. Kobayashi
ResearchOpen Access04 Apr 2024
Communications Biology

Volume: 7, P: 1-10
Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption

Brain-type creatine kinase (Ckb) has an unexpected role in bone biology. Decreasing its activity suppresses the bone-resorbing activity of osteoclasts, and mice lacking Ckb are protected from osteoporosis-inducing treatments. These findings identify Ckb as a new molecular against bone loss.

Eun-Ju Chang
Jeongim Ha
Hong-Hee Kim
Research24 Aug 2008
Nature Medicine

Volume: 14, P: 966-972
Simulating metabolic pathways to enhance interpretations of metabolome genome-wide association studies

Shun Kodate
Mitsuharu Sato
Kengo Kinoshita
ResearchOpen Access16 May 2025
Scientific Reports

Volume: 15, P: 1-11
C/EBPδ expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation

Sigal Gery
Sakae Tanosaki
H Phillip Koeffler
Research10 Jan 2005
Oncogene

Volume: 24, P: 1589-1597
Comparison of surgical outcomes for cervical radiculopathy by nerve root level

Masahito Oshina
Naohiro Kawamura
Yasushi Oshima
ResearchOpen Access14 Aug 2024
Scientific Reports

Volume: 14, P: 1-9
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17

Previous page
page 1
page 2
Next page

Search

Search articles by subject, keyword or author

Show results from

Advanced search

Quick links

Explore articles by subject
Find a job
Guide to authors
Editorial policies

Nature.com

nature.com sitemap

About Nature Portfolio

About us
Press releases
Press office
Contact us

Discover content

Journals A-Z
Articles by subject
protocols.io
Nature Index

Publishing policies

Nature portfolio policies
Open access

Author & Researcher services

Reprints & permissions
Research data
Language editing
Scientific editing
Nature Masterclasses
Research Solutions

Libraries & institutions

Librarian service & tools
Librarian portal
Open research
Recommend to library

Advertising & partnerships

Advertising
Partnerships & Services
Media kits
Branded content

Professional development

Nature Awards
Nature Careers
Nature Conferences

Regional websites

Nature Africa
Nature China
Nature India
Nature Japan
Nature Middle East

Privacy Policy
Use of cookies
Legal notice
Accessibility statement
Terms & Conditions
Your US state privacy rights

© 2025 Springer Nature Limited