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Showing 1–3 of 3 results
Advanced filters: Author: Sally-Ann Clark Clear advanced filters

  • Lineage tracing analyses of cells from two monozygotic twins presenting with myelofibrosis in adulthood provide evidence of in utero transplacental transmission of the tumorigenic clone.

    • Nikolaos Sousos
    • Máire Ní Leathlobhair
    • Adam J. Mead
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 1207-1211

  • The identification of a functionally distinct subset of haematopoietic stem cells (HSCs) that is primed for platelet-specific gene expression is described; the cells frequently have long-term myeloid lineage bias, can self-renew and give rise to lymphoid-biased HSCs, and may enable the design of therapies for enhancing platelet reconstitution.

    • Alejandra Sanjuan-Pla
    • Iain C. Macaulay
    • Sten Eirik W. Jacobsen
    Research
    Nature
    Volume: 502, P: 232-236