Nature Search

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

Neutralizing antibody responses of patients infected with SARS-CoV-2 peak at 3–4 weeks post onset of symptoms, then decline to low levels over the course of 3 months in some individuals.

Jeffrey Seow
Carl Graham
Katie J. Doores
Research26 Oct 2020
Nature Microbiology

Volume: 5, P: 1598-1607
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern

The authors assess the durability and long-term cross-reactivity of neutralizing antibodies raised in response to infections with SARS-CoV-2 or variants of concern in humans.

Liane Dupont
Luke B. Snell
Katie J. Doores
ResearchOpen Access15 Oct 2021
Nature Microbiology

Volume: 6, P: 1433-1442
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases

Hyo Won Jung
Su Jin La
Byoung Se Kwon
ResearchOpen Access01 Dec 2003
Experimental & Molecular Medicine

Volume: 35, P: 501-508
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19

Here the authors characterise the cellular and molecular progression of lung alveolar damage in severe COVID-19 patients using integrated histopathology and cell atlassing, pinpointing a role for macrophage SPP1 signalling to vasculature in this process.

Jimmy Tsz Hang Lee
Sam N. Barnett
Omer Ali Bayraktar
ResearchOpen Access10 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
A planet within the debris disk around the pre-main-sequence star AU Microscopii

A transiting planet with a period of about 8.5 days and a radius 0.4 times that of Jupiter is reported within the debris disk around the star AU Microscopii.

Peter Plavchan
Thomas Barclay
Perri Zilberman
Research24 Jun 2020
Nature

Volume: 582, P: 497-500
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Publisher Correction: A planet within the debris disk around the pre-main-sequence star AU Microscopii

Peter Plavchan
Thomas Barclay
Perri Zilberman
Amendments and Corrections15 Jul 2020
Nature

Volume: 583, P: E31
A protein complex required for polar growth of rhizobial infection threads

Many legumes accommodate rhizobial symbionts via transcellular infection threads. Here the authors show that in Medicago root hairs, polar growth of the infection thread requires a tip-localized protein complex consisting of VPY and VPY-like proteins that are stabilized by the E3 ligase LIN, as well as an exocyst complex subunit.

Cheng-Wu Liu
Andrew Breakspear
Jeremy D. Murray
ResearchOpen Access28 Jun 2019
Nature Communications

Volume: 10, P: 1-17
Strategies for making geoscience PhD recruitment more equitable

Admission to doctoral study is a crucial step in the academic pipeline, but discriminatory procedures can disproportionately impact students from ethnic minority backgrounds. We show how these policies contribute to inequity in the geosciences and propose strategies for change.

Benjamin Fernando
Sam Giles
Natasha Dowey
Comments & Opinion03 Aug 2023
Nature Geoscience

Volume: 16, P: 658-660
A UK perspective on tackling the geoscience racial diversity crisis in the Global North

Geoscientists will play key roles in the grand challenges of the twenty-first century, but this requires our field to address its past when it comes to diversity and inclusion. Considering the bleak picture of racial diversity in the UK, we put forward steps institutions can take to break down barriers and make the geosciences equitable.

Natasha Dowey
Jenni Barclay
Rebecca Williams
Comments & Opinion29 Apr 2021
Nature Geoscience

Volume: 14, P: 256-259
A wearable platform for closed-loop stimulation and recording of single-neuron and local field potential activity in freely moving humans

The Neuro-stack is a wearable platform for recording from single neurons in freely moving humans. It also allows for personalized stimulation during real-time decoding of neural activity.

Uros Topalovic
Sam Barclay
Dejan Markovic
ResearchOpen Access20 Feb 2023
Nature Neuroscience

Volume: 26, P: 517-527
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Benedict D. Michael
Cordelia Dunai
David K. Menon
Amendments and CorrectionsOpen Access04 Apr 2024
Nature Communications

Volume: 15, P: 1
Trends in incidence, prevalence, and survival of breast cancer in the United Kingdom from 2000 to 2021

Nicola L. Barclay
Edward Burn
Danielle Newby
ResearchOpen Access17 Aug 2024
Scientific Reports

Volume: 14, P: 1-16
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Oral prehabilitation for patients with head and neck cancer: getting it right - the Restorative Dentistry-UK consensus on a multidisciplinary approach to oral and dental assessment and planning prior to cancer treatment

Lorna K. McCaul
Stewart Barclay
Jose M. Rodriguez
ResearchOpen Access11 Nov 2022
British Dental Journal

Volume: 233, P: 794-800
Self care in patients with chronic heart failure

Heart failure is a chronic condition that requires a substantial amount of self care by patients. Dr. Riegel and colleagues review heart failure self care in terms of predictors and outcomes, and discuss their implications on clinical practice, public health and policy.

Barbara Riegel
Christopher S. Lee
Victoria Vaughan Dickson
Reviews19 Jul 2011
Nature Reviews Cardiology

Volume: 8, P: 644-654

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