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Advanced filters: Author: Sam Ghaffari-Kashani Clear advanced filters
  • Here, using deep mutagenesis and cryo-EM, the authors unveil an autoinhibited conformation of a clamp loader from T4 bacteriophage, which is characterized by disassembled catalytic sites and blocked DNA binding.

    • Kendra Marcus
    • Yongjian Huang
    • John Kuriyan
    Research
    Nature Structural & Molecular Biology
    Volume: 31, P: 424-435