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Showing 1–8 of 8 results
Advanced filters: Author: Sandile Cele Clear advanced filters
  • Cross-neutralization assays of early variants and the 501Y.V2 variant of SARS-CoV-2 show that plasma from individuals infected with 501Y.V2 effectively neutralizes all variants, indicating that a vaccine that targets 501Y.V2 may also be effective against other SARS-CoV-2 variants.

    • Sandile Cele
    • Inbal Gazy
    • Alex Sigal
    Research
    Nature
    Volume: 593, P: 142-146
  • Emerging SARS-CoV-2 Omicron sub-lineages BA.4 and BA.5 raise concerns about potential immune evasion. Here, Khan et al. show that both BA.4 and BA.5 are able to escape immune response induced by prior BA.1 infection, but that this effect is less pronounced in vaccinated individuals.

    • Khadija Khan
    • Farina Karim
    • Alex Sigal
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-7
  • The SARS-CoV-2 PANGO lineage C.1.2 has been under monitoring by global health authorities as it has spread worldwide. Here, Bhiman and colleagues characterise the emergence of the lineage, and its neutralisation sensitivity using data from vaccinees and previously infected individuals.

    • Cathrine Scheepers
    • Josie Everatt
    • Jinal N. Bhiman
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9
  • T cell responses to spike protein from the SARS-CoV-2 Omicron variant (B.1.1.529) are broadly similar to the responses to ancestral, Beta (B.1.351) and Delta (B.1.617.2) spike protein in vaccinated, infected and unvaccinated individuals.

    • Roanne Keeton
    • Marius B. Tincho
    • Catherine Riou
    ResearchOpen Access
    Nature
    Volume: 603, P: 488-492
  • A study quantifying the neutralization of severe acute respiratory syndrome coronavirus 2 variants in individuals infected with Omicron/BA.1 shows that vaccinated individuals previously infected with Omicron have enhanced protection against reinfection with current variants, \including Omicron/BA.2, while Omicron/BA.1 infected unvaccinated individuals have limited protection.

    • Khadija Khan
    • Farina Karim
    • Alex Sigal
    ResearchOpen Access
    Nature
    Volume: 607, P: 356-359
  • Plasma from individuals vaccinated with BNT162b2 exhibits 22-fold less neutralization capacity against Omicron (B.1.1.529) than against an ancestral SARS-CoV-2 strain but residual neutralization is maintained in those with high levels of neutralization of ancestral virus.

    • Sandile Cele
    • Laurelle Jackson
    • Alex Sigal
    ResearchOpen Access
    Nature
    Volume: 602, P: 654-656