Karnam et al. show that the β-catenin pathway is dispensable for the anti-inflammatory actions of intravenous immunoglobulin (IVIG) in human dendritic cells and in protecting against experimental autoimmune encephalomyelitis. This study implicates an unknown signaling pathway as a mediator of the anti-inflammatory effects of therapeutic IVIG.
- Anupama Karnam
- Naresh Rambabu
- Jagadeesh Bayry
