Nature Search

Correction: Corrigendum: Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

Dong-Chuan Guo
Hariyadarshi Pannu
Dianna M Milewicz
Amendments and Corrections01 Feb 2008
Nature Genetics

Volume: 40, P: 255
Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques

SARS-CoV-2 vaccines are needed to fight the pandemic. Here, authors show protective efficacy and immunogenicity of the inactivated SARS-CoV-2 vaccine BBV152 in rhesus macaques. This vaccine is currently in clinical development.

Pragya D. Yadav
Raches Ella
Balram Bhargava
ResearchOpen Access02 Mar 2021
Nature Communications

Volume: 12, P: 1-11
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21

Quinn T. Ostrom
Ben Kinnersley
Jill. S. Barnholtz-Sloan
ResearchOpen Access09 May 2018
Scientific Reports

Volume: 8, P: 1-15
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

Dong-Chuan Guo
Hariyadarshi Pannu
Dianna M Milewicz
Research11 Nov 2007
Nature Genetics

Volume: 39, P: 1488-1493
Protein-altering germline mutations implicate novel genes related to lung cancer development

In lung cancer, relatively few germline mutations are known to impact risk. Here the authors looked at rare variants in 39,146 individuals and find novel germline mutations associated with risk, as well as implicating ATM and a new candidate gene for lung cancer risk.

Xuemei Ji
Semanti Mukherjee
Christopher I. Amos
ResearchOpen Access11 May 2020
Nature Communications

Volume: 11, P: 1-14
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

A cross-ancestry genome-wide association meta-analysis of lung cancer including 61,047 cases and 947,237 controls identifies five new cross-ancestry susceptibility loci and highlights ancestry-specific effects of common and rare variants on lung cancer risk.

Jinyoung Byun
Younghun Han
Christopher I. Amos
Research01 Aug 2022
Nature Genetics

Volume: 54, P: 1167-1177
Epidemiology of Childhood Onset Essential Hypertension

Monesha Gupta-Malhotra
Sanjay Shete
Syed Shahrukh Hashmi
Research17 Sept 2018
Journal of Human Hypertension

Volume: 32, P: 808-813
Genome-wide association study identifies genes associated with neuropathy in patients with head and neck cancer

Cielito C. Reyes-Gibby
Jian Wang
Sanjay Shete
ResearchOpen Access08 Jun 2018
Scientific Reports

Volume: 8, P: 1-7
Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample

Paul M. Cinciripini
David W. Wetter
Sanjay Shete
ResearchOpen Access16 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients

Cielito C. Reyes-Gibby
Jian Wang
Sanjay Shete
ResearchOpen Access27 Sept 2016
Scientific Reports

Volume: 6, P: 1-6
Genome-wide association study identifies five susceptibility loci for glioma

Richard Houlston, Melissa Bondy and colleagues identify variants at five loci associated with glioma susceptibility, providing insights into the etiology of this primary brain tumor. The risk loci include common variants near TERT, CDKN2A-CDKN2B and RTEL1.

Sanjay Shete
Fay J Hosking
Richard S Houlston
Research05 Jul 2009
Nature Genetics

Volume: 41, P: 899-904
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

The role of impaired lung function in lung cancer etiology is complex due to the relation of cigarette smoking to both conditions. Here, supported by Mendelian randomization analysis the authors find a link between pulmonary function impairment and lung cancer risk beyond smoking, implicating immune-related pathways

Linda Kachuri
Mattias Johansson
Rayjean J. Hung
ResearchOpen Access07 Jan 2020
Nature Communications

Volume: 11, P: 1-14
Targeted Sequencing in Chromosome 17q Linkage Region Identifies Familial Glioma Candidates in the Gliogene Consortium

Ali Jalali
E. Susan Amirian
Melissa L. Bondy
ResearchOpen Access05 Feb 2015
Scientific Reports

Volume: 5, P: 1-8
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

Beatrice Melin, Richard Houlston, Melissa Bondy and colleagues report results of a large-scale genome-wide association study of glioma. They identify five new risk loci for glioblastoma and eight new risk loci for non-glioblastoma tumors, highlighting distinct genetic etiologies for these two glioma subtypes.

Beatrice S Melin
Jill S Barnholtz-Sloan
Melissa L Bondy
Research27 Mar 2017
Nature Genetics

Volume: 49, P: 789-794
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

Christopher I Amos
Xifeng Wu
Richard S Houlston
Research02 Apr 2008
Nature Genetics

Volume: 40, P: 616-622
Genetic susceptibility to patient-reported xerostomia among long-term oropharyngeal cancer survivors

Puja Aggarwal
Katherine A. Hutcheson
Sanjay Shete
ResearchOpen Access22 Apr 2022
Scientific Reports

Volume: 12, P: 1-12
Genetic linkage and imprinting effects on body mass index in children and young adults

Olga Y Gorlova
Christopher I Amos
Eric Boerwinkle
Research28 May 2003
European Journal of Human Genetics

Volume: 11, P: 425-432

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Correction: Corrigendum: Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

Protein-altering germline mutations implicate novel genes related to lung cancer development

Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

Epidemiology of Childhood Onset Essential Hypertension

Genome-wide association study identifies genes associated with neuropathy in patients with head and neck cancer

Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample

Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients

Genome-wide association study identifies five susceptibility loci for glioma

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Targeted Sequencing in Chromosome 17q Linkage Region Identifies Familial Glioma Candidates in the Gliogene Consortium

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

Genetic susceptibility to patient-reported xerostomia among long-term oropharyngeal cancer survivors

Genetic linkage and imprinting effects on body mass index in children and young adults

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