The genetic ion channelopathies comprise a new and expanding field of neurological diseases. This Review focuses on the voltage-gated P/Q-type calcium channel, and specifically on inherited mutations in the gene encoding the α1 subunit. The authors consider various conditions arising from channel dysfunction, including episodic ataxia type 2, familial hemiplegic migraine-1 and spinocerebellar ataxia type 6.
- Sanjeev Rajakulendran
- Diego Kaski
- Michael G. Hanna
