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Showing 51–100 of 183 results

Advanced filters: Author: Santosh Kumar Clear advanced filters

Activation of diverse signalling pathways by oncogenic PIK3CA mutations

Mutations in PIK3CA, a catalytic subunit of PI3 kinase, are linked to deregulation of Akt-mTOR signalling in many cancers. Here, using a SILAC-based quantitative proteomic approach, the authors discover six new AKT1 substrates, including the actin regulator cortactin.

Xinyan Wu
Santosh Renuse
Akhilesh Pandey
Research23 Sept 2014
Nature Communications

Volume: 5, P: 1-13
Polystyrene adsorbents: rapid and efficient surrogate for dialysis in membrane protein purification

Santosh Kumar Palanirajan
Punitha Govindasamy
Sathyanarayana N. Gummadi
ResearchOpen Access01 Oct 2020
Scientific Reports

Volume: 10, P: 1-9
Foxd4l1.1 negatively regulates transcription of neural repressor ventx1.1 during neuroectoderm formation in Xenopus embryos

Shiv Kumar
Zobia Umair
Jaebong Kim
ResearchOpen Access08 Oct 2020
Scientific Reports

Volume: 10, P: 1-15
Noise-resilient single-pixel compressive sensing with single photon counting

Single-photon imaging and sensing promise great advantages over their classical counterparts, but their practical uses are easily compromised by ambient and quantum noises. The authors demonstrate a noise-resilient scheme based on single-pixel compressive sensing and single-photon counting, achieving high performance via quantum parametric mode sorting.

Lili Li
Santosh Kumar
Yu-Ping Huang
ResearchOpen Access29 Mar 2024
Communications Physics

Volume: 7, P: 1-8
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Towards spontaneous parametric down conversion from monolayer MoS₂

Hatef Dinparasti Saleh
Stefano Vezzoli
Daniele Faccio
ResearchOpen Access01 Mar 2018
Scientific Reports

Volume: 8, P: 1-7
Causes and consequences of child growth faltering in low-resource settings

Analysis of data from 33 longitudinal cohorts from low- and middle-income countries indicates that conditions during pre-conception, pregnancy and the first few months of life are crucial in determining the risk of growth faltering in young children.

Andrew Mertens
Jade Benjamin-Chung
Pablo Penataro Yori
ResearchOpen Access13 Sept 2023
Nature

Volume: 621, P: 568-576
Early-childhood linear growth faltering in low- and middle-income countries

A pooled analysis of longitudinal studies in low- and middle-income countries identifies the typical age of onset of linear growth faltering and investigates recurrent faltering in early life.

Jade Benjamin-Chung
Andrew Mertens
Pablo Penataro Yori
ResearchOpen Access13 Sept 2023
Nature

Volume: 621, P: 550-557
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode proteins potentially related to kidney development.

Cristian Pattaro
Alexander Teumer
Caroline S. Fox
ResearchOpen Access21 Jan 2016
Nature Communications

Volume: 7, P: 1-19
Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress

Modar Kassan
Ajit Vikram
Kaikobad Irani
ResearchOpen Access09 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
Discerning the differential molecular pathology of proliferative middle ear lesions using Raman spectroscopy

Rishikesh Pandey
Santosh Kumar Paidi
Ishan Barman
ResearchOpen Access20 Aug 2015
Scientific Reports

Volume: 5, P: 1-8
Ultrafast Energy Transfer in Ultrathin Organic Donor/Acceptor Blend

Ajay Ram Srimath Kandada
Giulia Grancini
Guglielmo Lanzani
ResearchOpen Access25 Jun 2013
Scientific Reports

Volume: 3, P: 1-7
Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine

Debendra Muduli
Rani Kumari
Dinesh Kumar Sah
ResearchOpen Access29 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells

Although phagocytic clearance of apoptotic germ cells by Sertoli cells is essential for spermatogenesis, little of the mechanism is known. Here the authors show that Sertoli cells employ LC3-associated phagocytosis (LAP) by recruiting autophagy member proteins to clear apoptotic germ cells.

Subbarayalu Panneerdoss
Suryavathi Viswanadhapalli
Manjeet K. Rao
ResearchOpen Access19 Sept 2017
Nature Communications

Volume: 8, P: 1-14
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Approaching a discussion on the detachment of chlorpyrifos in contaminated water using different leaves and peels as bio adsorbents

Varsha Joshi
Manoj Kumar Jindal
Santosh Kumar Sar
ResearchOpen Access11 Jul 2023
Scientific Reports

Volume: 13, P: 1-20
Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail

Santosh Kumar Prajapati
Shaohua Wang
Hariom Yadav
ResearchOpen Access10 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
A privacy-preserving dependable deep federated learning model for identifying new infections from genome sequences

Sk. Tanzir Mehedi
Lway Faisal Abdulrazak
Fahad Ahmed Al-Zahrani
ResearchOpen Access01 Mar 2025
Scientific Reports

Volume: 15, P: 1-24
Arsenic causing gallbladder cancer disease in Bihar

Arun Kumar
Mohammad Ali
Ashok Kumar Ghosh
ResearchOpen Access14 Mar 2023
Scientific Reports

Volume: 13, P: 1-16
Spatio-temporal epidemiology and associated indicators of COVID-19 (wave-I and II) in India

Karuppusamy Balasubramani
Venkatesh Ravichandran
Praveen Balabaskaran Nina
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-12
Ammonia transformation by potential consortium in the aquatic system

Anne Bhambri
Santosh Kumar Karn
Arun Kumar
ResearchOpen Access19 Feb 2025
Scientific Reports

Volume: 15, P: 1-12
Nanotherapy: targeting the tumour microenvironment

In this Journal Club, S. K. Singh and R. Singh discuss a study that used bioreactive, tumour microenvironment-modulating nanoparticles with doxorubicin to treat breast tumour xenograft-bearing mice, leading to reversal of immunosuppression and tumour shrinkage.

Santosh Kumar Singh
Rajesh Singh
Research Highlights02 Mar 2022
Nature Reviews Cancer

Volume: 22, P: 258
Effects of COVID-19 pandemic on low birth weight in a nationwide study in India

Kumar et al. examine differences in birthweight and LBW between the pre COVID-19 (before Jan 2020) and COVID-19 (after March 2020 onwards). Infants born during the COVID-19 period had lower birthweight compared to infants born during pre-COVID-19 periods.

Santosh Kumar
Clare Hill
Timothy J. Halliday
ResearchOpen Access14 Jun 2024
Communications Medicine

Volume: 4, P: 1-7
Arsenic exposure in Indo Gangetic plains of Bihar causing increased cancer risk

Arun Kumar
Mohammad Ali
Ashok Kumar Ghosh
ResearchOpen Access27 Jan 2021
Scientific Reports

Volume: 11, P: 1-16
Large trion binding energy in monolayer WS₂ via strain-enhanced electron–phonon coupling

Two-dimensional transition metal dichalcogenides are a promising optoelectronic platform for exploring excitonic and many-body physics. Here, the authors investigate the effects of nanoparticle-induced strain engineering of monolayer WS₂, demonstrating high tunability of excitonic emission energies and trion’s binding energy due to strain-enhanced electron–phonon coupling.

Yunus Waheed
Sumitra Shit
Santosh Kumar
ResearchOpen Access29 Apr 2025
Communications Materials

Volume: 6, P: 1-8
Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel

Intracellular trafficking of the voltage-gated cardiac Na⁺ channel Nav1.5 is regulated by lysine deacetylation mediated by Sirt1, thereby affecting sodium current and cardiac electrical activity.

Ajit Vikram
Christopher M Lewarchik
Kaikobad Irani
Research13 Feb 2017
Nature Medicine

Volume: 23, P: 361-367
Artificial neural network detection of pancreatic cancer from proton (1H) magnetic resonance spectroscopy patterns of plasma metabolites

Solaiyappan et. al apply AI to analyze metabolic information contained in 1H magnetic resonance spectra to distinguish between pancreatic cancer and non-disease participants. This work presents a biofluid-based assay capable of screening for pancreatic disease and cancer.

Meiyappan Solaiyappan
Santosh Kumar Bharti
Zaver M. Bhujwalla
ResearchOpen Access21 Jan 2025
Communications Medicine

Volume: 5, P: 1-10
Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication

Sanjana Haque
Namita Sinha
Santosh Kumar
ResearchOpen Access23 Nov 2017
Scientific Reports

Volume: 7, P: 1-14
Geospatial methodology for determining the regional prevalence of hospital-reported childhood intussusception in patients from India

Shikha Dixit
Manoja Kumar Das
Saurabh Garge
ResearchOpen Access20 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Genetic and structural insights into the functional importance of the conserved gly-met-rich C-terminal tails in bacterial chaperonins

The E. coli chaperonin GroEL forms nano-cages for protein folding. Bacterial chaperonin paralogues exhibit divergence at their C-terminus. Here, the authors demonstrate that the Gly-Met-rich C-termini are functionally significant in protein folding.

C. M. Santosh Kumar
Aisha M. Mai
Peter A. Lund
ResearchOpen Access08 Apr 2025
Communications Biology

Volume: 8, P: 1-12
Evolution of genes and genomes on the Drosophila phylogeny

An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

Andrew G. Clark
Michael B. Eisen
Iain MacCallum
Research08 Nov 2007
Nature

Volume: 450, P: 203-218
Novel peptide inhibitor of human tumor necrosis factor-α has antiarthritic activity

Debasis Sahu
Charu Gupta
Chuan-Ju Liu
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-14
Computational drug repurposing study elucidating simultaneous inhibition of entry and replication of novel corona virus by Grazoprevir

Santosh Kumar Behera
Nazmina Vhora
Alok Jain
ResearchOpen Access31 Mar 2021
Scientific Reports

Volume: 11, P: 1-11
Investigation of Bi₂MoO₆/MXene nanostructured composites for photodegradation and advanced energy storage applications

Sagarika Panda
Savita Mehlawat
Amit Sanger
ResearchOpen Access09 Nov 2024
Scientific Reports

Volume: 14, P: 1-23
Epistatic interactions of major effect drought QTLs with genetic background loci determine grain yield of rice under drought stress

Shailesh Yadav
Nitika Sandhu
Arvind Kumar
ResearchOpen Access22 Feb 2019
Scientific Reports

Volume: 9, P: 1-13
Controlled release herbicide formulation for effective weed control efficacy

Santosh Kumar Paul
Yunfei Xi
Ravi Naidu
ResearchOpen Access20 Feb 2024
Scientific Reports

Volume: 14, P: 1-10
Phenotype puzzle: the role of novel LMBRD1 gene variant in Cbl deficiency causing Dyskeratosis Congenita-like clinical manifestations

Anjali Shah
Santosh Khuba
Babu Rao Vundinti
Research13 Feb 2025
Journal of Human Genetics

Volume: 70, P: 207-213
A polymorphic (GA/CT)n- SSR influences promoter activity of Tryptophan decarboxylase gene in Catharanthus roseus L. Don

Santosh Kumar
Sabhyata Bhatia
ResearchOpen Access13 Sept 2016
Scientific Reports

Volume: 6, P: 1-12
RNA-seq analysis reveals the genes/pathways responsible for genetic plasticity of rice to varying environmental conditions on direct-sowing and transplanting

Suresh Kumar
Karishma Seem
Trilochan Mohapatra
ResearchOpen Access10 Feb 2022
Scientific Reports

Volume: 12, P: 1-22
The role of community mobilization in people’s healthcare-seeking behavior during the COVID-19 vaccination journey: select case studies from Madhya Pradesh

Priyanka Das
Santosh Shukla
Raj Shankar Ghosh
ResearchOpen Access20 Jun 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-11
Relationship between adolescent anemia and school attendance observed during a nationally representative survey in India

De Neve et al. determine the relationship between anemia and school attendance among adolescents using a large national dataset from India. In this within-household analysis, the relationship between anemia and schooling is more muted compared to more conventional analyses which do not account for all household-level factors.

Jan-Walter De Neve
Omar Karlsson
Sebastian Vollmer
ResearchOpen Access12 Jun 2024
Communications Medicine

Volume: 4, P: 1-9
Author Correction: Antimicrobial and antioxidant study of combined essential oils of Anethum Sowa Kurz. and Trachyspermum ammi (L.) along with quality determination, comparative histo-anatomical features, GC‒MS and HPTLC chemometrics

S.A. Wasim Akram
Mary Shamya Arokiarajan
Kabiruddin Ahmed K
Amendments and CorrectionsOpen Access06 Feb 2025
Scientific Reports

Volume: 15, P: 1-2
Author Correction: Early-childhood linear growth faltering in low- and middle-income countries

Jade Benjamin-Chung
Andrew Mertens
Pablo Penataro Yori
Amendments and CorrectionsOpen Access13 Oct 2023
Nature

Volume: 623, P: E2
Implementing sustainable practices to combat root knot nematode infestation in tomato farming from Meghalaya

H. Jeevan
Raghubir Kumar Patidar
N. S Nysanth
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-12
Xbra modulates the activity of linker region phosphorylated Smad1 during Xenopus development

Santosh Kumar
Zobia Umair
Jaebong Kim
ResearchOpen Access18 Apr 2024
Scientific Reports

Volume: 14, P: 1-14
Deciphering the genetic basis of root morphology, nutrient uptake, yield, and yield-related traits in rice under dry direct-seeded cultivation systems

Nitika Sandhu
Sushil Raj Subedi
Arvind Kumar
ResearchOpen Access27 Jun 2019
Scientific Reports

Volume: 9, P: 1-16
Characterization and evaluation of mycosterol secreted from endophytic strain of Gymnema sylvestre for inhibition of α-glucosidase activity

Amit Ranjan
Rajesh Kumar Singh
Santosh Kumar Singh
ResearchOpen Access21 Nov 2019
Scientific Reports

Volume: 9, P: 1-13
Development of renewable energy fed three-level hybrid active filter for EV charging station load using Jaya grey wolf optimization

Koganti Srilakshmi
D. Teja Santosh
Baseem Khan
ResearchOpen Access23 Feb 2024
Scientific Reports

Volume: 14, P: 1-23
Author Correction: Early-childhood linear growth faltering in low- and middle-income countries

Jade Benjamin-Chung
Andrew Mertens
Pablo Penataro Yori
Amendments and CorrectionsOpen Access12 Dec 2024
Nature

Volume: 637, P: E18
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Georg B. Ehret
Patricia B. Munroe
Toby Johnson
Research11 Sept 2011
Nature

Volume: 478, P: 103-109

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