Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Sara Alaei Clear advanced filters

  • Exhaustion is a functional state that hampers anti-cancer and antiviral CD8 T cell activity, and is preceded by a stem-like state, maintained by the transcription factor TCF1. Here authors develop mouse models that allow a precise understanding of the developmental trajectory between the stem-cell-like and exhausted states of CD8 T cells and find that while constitutive overexpression of TCF1 expands the stem-like T cell pool, TCF1 expression specifically in already exhausted cells is unable to promote dedifferentiation.

    • Maria N. de Menezes
    • Amanda X. Y. Chen
    • Ian A. Parish
    ResearchOpen Access
    Nature Communications
    P: 1-15

  • There is high prevalence of whole genome duplication (WGD) in high grade serous ovarian cancer. Here, the authors compare tumours with and without WGD and find that those that acquired WGD early during tumour evolution are associated with worse survival and have the lowest expression of MHC-II.

    • Nikki L. Burdett
    • Madelynne O. Willis
    • Elizabeth L. Christie
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • Jones et al. examine the generalizability of the valence–dominance model of social judgements of faces in 41 countries across 11 world regions. They find evidence of both generalizability and variation, depending on the analytical method.

    • Benedict C. Jones
    • Lisa M. DeBruine
    • Nicholas A. Coles
    Research
    Nature Human Behaviour
    Volume: 5, P: 159-169

  • A new somite compartment, called the endotome, that contributes to the formation of the embryonic dorsal aorta by providing endothelial progenitors is identified here; endotome-derived endothelial progenitors, whose formation is regulated by the activity of the meox1 gene, induce haematopoietic stem cell formation upon colonization of the nascent dorsal aorta.

    • Phong Dang Nguyen
    • Georgina Elizabeth Hollway
    • Peter David Currie
    Research
    Nature
    Volume: 512, P: 314-318